Mechanism That Leads to Sporadic Parkinson’s Disease Identified
 

Great news
 

Hi Soccertese,
thanks a lot to report this beautiful news.

I am very happy to see again some research pointing at alpha synuclein. There are many agents entering clinical testing that intend to remove this protein. This is hope giving.

In the article referenced by Soccertese:

'“Furthermore, we found that exposure to toxins associated with Parkinson's can increase the abundance of this longer transcript form of alpha-synuclein. Thus, this mechanism may represent a common pathway by which environmental and genetic factors impact the disease,” said Dr. Abeliovich.'

This is consistent with my take on the spatial epidemiological data:
- people onset younger in "bad" areas.
- people progress faster in "bad" areas.

John