Annals of Neurology [2009] 66 (5) : 591-596 (Olanow CW, Kordower JH, Lang AE,
Obeso JA.) Complete abstract

excerpt from the conclusion....what a surprise [she says dryly]. And that was our only issue for 10{?} years. support it or be called a radical right religious fanatic and not worth even listening to. the world is starting to really **** me off. i'm in a "mood" now peg if you are reading this. But with good reason. Some of us knew inside that it wasn't natural and went against our "gut" and beliefs to try to believe that it was ok. in a sense, i sold out. I will not do that again for any theory or politically correct bs.....afraid to ask...but are they talking about cell implants or does that also include growth factors?....paula

begin excerpt:

The failure of dopaminergic cell-based therapies to achieve efficacy in double blind clinical trials, the development of unanticipated and occasionally disabling side effects, evidence that implanted cells themselves can develop the pathological changes of PD, and the likelihood that these treatments will not address the nondopaminergic features of the disease do not bode well for the near-term future of cell-based therapies as a clinically meaningful treatment for the majority of patients with PD. For the present, it would seem that greater opportunities for more effective therapies in PD would derive from better understanding of the etiology and pathogenesis of the disease and the development of neuroprotective therapies that might slow or stop disease progression."

Originally Posted by paula_w (Post 594298) Annals of Neurology [2009] 66 (5) : 591-596 (Olanow CW, Kordower JH, Lang AE, Obeso JA.) Complete abstract excerpt from the conclusion....what a surprise [she says dryly]. And that was our only issue for 10{?} years. support it or be called a radical right religious fanatic and not worth even listening to. the world is starting to really **** me off. i'm in a "mood" now peg if you are reading this. But with good reason. Some of us knew inside that it wasn't natural and went against our "gut" and beliefs to try to believe that it was ok. in a sense, i sold out. I will not do that again for any theory or politically correct bs.....afraid to ask...but are they talking about cell implants or does that also include growth factors?....paula begin excerpt: The failure of dopaminergic cell-based therapies to achieve efficacy in double blind clinical trials, the development of unanticipated and occasionally disabling side effects, evidence that implanted cells themselves can develop the pathological changes of PD, and the likelihood that these treatments will not address the nondopaminergic features of the disease do not bode well for the near-term future of cell-based therapies as a clinically meaningful treatment for the majority of patients with PD. For the present, it would seem that greater opportunities for more effective therapies in PD would derive from better understanding of the etiology and pathogenesis of the disease and the development of neuroprotective therapies that might slow or stop disease progression."