NeuroTalk Support Groups - Anyone tried this supplement?

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Anyone tried this supplement?

Quote:

There is no reliable evidence that corydalis or its constituents offer any medicinal benefits. Corydalis contains a number of active and potentially dangerous chemicals in the alkaloid family, including tetrahydropalmatine (THP), corydaline, protopine, tetrahydrocoptisine, tetrahydrocolumbamine, and corybulbine. Of these, THP may be the most active, as well as the most toxic (see Safety Issues ).
http://www.med.nyu.edu/content?ChunkIID=104681

I can't find enough credible information about this supplement to say with any confidence that I think it can't hurt to try it.

There has been one study (done on rodents) of a compound—Dehydrocorybulbine (DHCB)—derived from the plant that has shown some promise, but that is still a long way off.

Quote:

DHCB needs to be evaluated for any toxicity before it can be developed as a drug.
http://news.uci.edu/press-releases/c...ropathic-pain/

It is widely use in Chinese medicine and is usually combined with other herbs. I would suggest looking at the more traditional sources on it's use and dosage instead of relying on western medical sources. Eastern/Chinese Medicine does not alway translate well in our medical model.

No haven't tried it. I am all for natural remedies, but just because it is natural does not make it safe. These two statements do not jive for me:

..."much of the modern research done on corydalis so far is still in early stages.", "Corydalis is generally considered to be safe for healthy adults..."

You might want to look into the human studies, if any, and see what the side effects were.
Ron