NeuroTalk Support Groups - Parkinson's & Prednisone

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- - Parkinson's & Prednisone (https://www.neurotalk.org/parkinson-s-disease/118588-parkinsons-prednisone.html)

Parkinson's & Prednisone

Just wanted to forward my experience with Prednisone. Dr. prescribed it to combat a serious outbreak of Psoriasis as follows;

Take six 5 mgs of APO-Prednisone in am daily for 7 days.
Take four 5 mgs daily for 4 days
Take two 5 mgs daily for 3 days.

Within 6 hrs of 1st dose, I could feel an improvement generally in my well being. Between 24-30 hrs PD symptoms had diminished noticeably. At approx. 48 hrs I FELT NORMAL and estimate 90% reduction in symptoms. Only a minor twitch in my left hand remained. Gone was the slow walk, weakness, bent neck, & slow speech. My strength and attitude returned to normal and I was able to go out on my ATV and clear a 1/2 mile of bush trails that I started a yr or so ago.

Even as the doseage decreased to the 4, 5mg, pills a day the positive effects continued till the 2nd day of two pills a day and thats when the symptoms slowly started to return.

Only negative side effect was increased blood sugar levels - pretty high - but that can be treated. And for as good as I felt, I"ll take the diabetic risk. I've had diabetes for 20 yrs.

I'm going to the Dr. today to discuss the possibility of treatment with Prednisone.

I emailed my experience to every PD researcher I could find on the net.

I hope this info will be of interest to you.

HM

Here is my take on this. Prednisone is a steroidal anti-inflammatory. As such, it decreased the cytokine output by the brain's microglia (thereby promoting neurofunction), closed the BBB, and had a similar effect on the wall of the gut (thus decreasing the brain's toxin load). Our bodies try to do the same by using cortisol.

Unfortunately, both have problems over the long haul. Artificial steroids can only be used for a short term. Natural ones eventually take their own toll plus exhaust the adrenals where they are made.

Please keep us informed on this one.

Quote:

Originally Posted by HarryM (Post 640910)

Now this is a little spooky

One year ago exactly, we discussed a similar experience

http://neurotalk.psychcentral.com/thread83577.html

Thanks for posting Harry and give us an update please.

paula

Quote:

Originally Posted by HarryM (Post 640910)

Just wanted to forward my experience with Prednisone. Dr. prescribed it to combat a serious outbreak of Psoriasis as follows;

Take six 5 mgs of APO-Prednisone in am daily for 7 days.
Take four 5 mgs daily for 4 days
Take two 5 mgs daily for 3 days.

Within 6 hrs of 1st dose, I could feel an improvement generally in my well being. Between 24-30 hrs PD symptoms had diminished noticeably. At approx. 48 hrs I FELT NORMAL and estimate 90% reduction in symptoms. Only a minor twitch in my left hand remained. Gone was the slow walk, weakness, bent neck, & slow speech. My strength and attitude returned to normal and I was able to go out on my ATV and clear a 1/2 mile of bush trails that I started a yr or so ago.
Harry,

Even as the doseage decreased to the 4, 5mg, pills a day the positive effects continued till the 2nd day of two pills a day and thats when the symptoms slowly started to return.

Only negative side effect was increased blood sugar levels - pretty high - but that can be treated. And for as good as I felt, I"ll take the diabetic risk. I've had diabetes for 20 yrs.

I'm going to the Dr. today to discuss the possibility of treatment with Prednisone.

I emailed my experience to every PD researcher I could find on the net.

I hope this info will be of interest to you.

HM

Harry,
My old dog has been given a course of prednisone for seizures 3 times and goes from acting like old dogs do to a young thing in no time!
My husband thinks I should try some!

animals and pred

Quote:

Originally Posted by made it up (Post 641231)

Harry,
My old dog has been given a course of prednisone for seizures 3 times and goes from acting like old dogs do to a young thing in no time!
My husband thinks I should try some!

typically cats and dogs can tolerate prednisone much better than humans and don't develop the nasty side effects which make them such a mixed blessing for us. i knew one cat who was deteriorating quickly at the age of 17. the vet put him on a daily dose of pred, and that cute old guy lasted another 5 years. now if i could only figure out a way to grow fur and a tail . . .