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-   -   High On Dopamine? (https://www.neurotalk.org/parkinson-s-disease/6741-dopamine.html)

lou_lou 11-19-2006 05:22 PM

High On Dopamine?
 
http://www.utexas.edu/research/asrec/neuron.html


DOPAMINE the effects of - both /good and the bad...

HIGH ON DOPAMINE

Dopamine is an important brain chemical involved in motor functions and general arousal. Dopamine is also involved in the ability to learn and the encoding of stimuli. Virtually all drugs of abuse, including heroin and other opiates, alcohol, cocaine, amphetamine and nicotine activate dopamine neuronal systems. So called "natural" rewards such as food, positive social interactions and even humor, likewise activate dopamine neurons and are powerful aids to attention and learning. Sweet solutions are a well-characterized natural reward. When a source of sugar is encountered, animals will consume substantial amounts, return to it preferentially, and will work to obtain access.
A number of psychiatric disorders are associated with imbalances with dopamine, particularly schizophrenia, Parkinson’s disease, and mood disorders, including certain types of depression. Dopamine may also be involved in restless legs syndrome.

High on Dopamine
Temporary elevation of dopamine levels often leads to an improvement in mood, alertness, libido, and perhaps even an enhancement in verbal fluency and creativity. However, a dopamine increase can lead to side effects to including the propensity to have an addictive behavior. For instance, there have been a few reports that patients with Parkinson's disease became involved in gambling when the dosage of their dopamine-enhancing medicines was increased. Interestingly, dopamine at times may lead to a sleepy state.

How is Dopamine made?
Dopamine is made from the amino acid tyrosine. Once produced, dopamine can, in turn, convert into the brain chemicals norepinephrine and epinephrine.


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