Vitamin B's make me feel worse
 

I have all over body burning and when I take any Vitamin B's I get worse burning. I believe it is because the Vitamin B's create more blood circulation and that vasodialation make me feel worse. This seems to me indicate that my burning is caused by a vascular issue.

Exactly which B's? Niacin, B3 (but not niacinamide form) causes flushing/vasodilation.

The others are less likely. But high dose B6 over 100mg a day may cause some neuropathic symptoms in some people.

B6 also facilitates serotonin manufacture and serotonin has a flushing capacity when present in large amounts... SSRI drugs can do the same.

Benfotiamine B1-even as low as 25 mg.
Thiamine -25 mg
B12-1000 mg

All of the above make me burn like crazy. So, this has to somehow be a clue into what is causing this condition I have, but when I mention it to the Dr.s they just ignore it.

Is the B12 methyl type or cyano? Cyano is synthetic and some people cannot tolerate it or activate it.

I have never seen anyone get more symptoms from those you list. However, rose, who used to post here claimed that people who start with B12 who were very low to start, often get temporary painful symptoms when they start to heal.

I know when I started my thyroid medication, my feet had gone pretty numb by then. I had been hypo most of my adult life.
The whole first year on the levothyroxine, and my feet "woke up" and tingled/burned for a long time until they were back to normal. This is like when you get very cold hands out in the snow, and warm up....you get red and tingle/burn....it was like that only 24/7 for a year! That didn't involve ANY vitamins, as I didn't have the training yet for that and wasn't doing supplements yet. (this was almost 20 yrs ago). But it does illustrate the concept of healing and odd sensations, that rose claimed she had while improving her combined degeneration of the spinal cord with B12.

Its the Methyl type of B12.

Alot of people with Erythromelalgia have the same problem with the B vitamins too. I have EM, so its interesting.....don't know what it all means but it has to mean something!

Are you doing the magnesium? That is a suggested treatment for EM you know.

Do you know your B12 serum level? If it is not low, then you don't need to take the B12 if it bothers you. But I would look at this carefully, and see if with time, you could sustain it.

If you have not had the DNA tests for the MTHFR mutations, you don't know if you are not converting folate to active methylfolate in the body. This is a pretty common genetic problem. 10% at least in US, and one doctor came on one of my threads here and suggested new data that up to 30% have this genetic failure. If you do and cannot use the folic acid in your food or supplements you might try taking the B12 with l-methylfolate. Solgar makes it OTC and is the most affordable. It is called Metafolin by some. The RX vitamin Metanx has both methylfolate and methy B12 in it, for this reason.