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-   -   anyone ever use doxepin/seraquel? (https://www.neurotalk.org/peripheral-neuropathy/108784-doxepin-seraquel.html)

antonina 11-22-2009 08:01 PM

anyone ever use doxepin/seraquel?
 
New neuro prescribed it 2 weeks ago. I'm just on 20 mg. per night. It lets me sleep soundly and even if I wake up to use the loo, I can fall right back.

The doc said he's dx'ing it instead of elavil which had caused a lot of brain fog when I took it about 4 years ago. My main issue with doxepin is that it causes pulsating, tremory feelings throughout my body which are quite unpleasant. Doc confirmed that this is one of its side effects.

Does anyone have any experience with this drug? I'm thinking of getting off it because of the internal shakiness.

pabb 11-23-2009 08:02 AM

Quote:

Originally Posted by antonina (Post 592593)
New neuro prescribed it 2 weeks ago. I'm just on 20 mg. per night. It lets me sleep soundly and even if I wake up to use the loo, I can fall right back.

The doc said he's dx'ing it instead of elavil which had caused a lot of brain fog when I took it about 4 years ago. My main issue with doxepin is that it causes pulsating, tremory feelings throughout my body which are quite unpleasant. Doc confirmed that this is one of its side effects.

Does anyone have any experience with this drug? I'm thinking of getting off it because of the internal shakiness.

doxepin and seroquel are two different drugs, the first is an antidepressant and the second an antipsychotic.....i would think it was the former??

mrsD 11-23-2009 08:34 AM

I took doxepin 2 decades ago for a bad sciatica attack. I was working midnights then too...it was stressful on my body.

I took 20mg also (2 x10mg capsules). It helped my pain quite a bit, but only helped with sleeping so so. The sciatica eventually cleared up when I resumed a regular working schedule.

I took it for about 2 yrs. The only side effect I had was some blurring of vision. I don't recall vibrating feelings at all.
This was before I had my hypothyroid fixed. So I still had my severely affected feet too.

antonina 11-23-2009 10:14 AM

It's doxepin. I don't know why I wrote Seraquel.

I just spoke w/ neuro and told him I wanted off this because even tho I am now taking 10 mg., I still have that vibration thing. He said he has patients who are taking 300 mg. pd!!

Back to the drawing board.

mrsD 11-23-2009 10:21 AM

150mg to 300mg a day is the antidepressant dose.

The lower doses typically are used for chronic pain.
This drug takes more than 2 weeks to give any results IMO.

LizaJane 11-23-2009 10:57 AM

Low doses of Sinequan, like Elavil, are excellent for deepening sleep, so you wake up less often, and can feel more rested. It can help people sleep THROUGH pain quite nicely. I've take 10-30mg of Elavil for years now, it's a been wonderful for me. While it is helpful in lowering pain, also, you have to give it a bit of time for this.

All the antidepressants interfere with pain pathways, and are one part of a good drug plan to attack pain pathways from different directions.

Seroquel is MARKETED as an anti-psychotic, but that should not make anyone who is on it worried that their doctor thinks they are psychotic. Over the years it became clear that it is excellent for anxiety and mood disorders, and it is mostly used for that, in doses of 25 - 100 mg. With Seroquel, in higher doses, it's important to have your weight monitored, as, on the heftier doses, their can be a lot of weight gain. Low doses don't seem much of a problem with this.

echoes long ago 11-23-2009 12:58 PM

Mrs. D did going back to work and moving around more help your sciatica to clear up? That is what i got from your post. Now that this sciatica attack i am in the midst of has lessened i find i feel better if i move around during the day. not too much walking but moving around is making it feel better, though i still have that additional degree of numbness from mid calf through ankle and inability to raise my front foot off the ground.

At times i understand why doctors dont understand what we are talking about. For instance now, while normally my both legs from the calf down through the feet are numb and a greater degree of numbness from above the ankle through the toes, now the left is the same as normal but the right is more numb than usual even though the usual includes walking around with a thumb tack in my foot without feeling it. Try explaining all of that....ha

mrsD 11-23-2009 02:19 PM

No, I was always working ...I just retired 2 yrs ago or so. I was in my 40's and still "young".

I think it was the stool, that I used at that store sometimes. I'd do paperwork sitting on it. I think stools, are hard on the nerve as it goes thru the butt muscles.
My midnights was 10pm to 9am 7 days in a row, and then off 7 days.

The first year wasn't too bad on me, the second year, I had a gout attack in my foot, shingles, and pneumonia. My doctor said NO MORE midnights. I just assumed the sciatica was part of all that...it was only in the left leg. This was long before I discovered magnets. I bet they would have worked on it faster!

I only had pain, no numbness. I recall alot of pain, and limping.
When I went out in the mornings at the end of my shift, the morning clerks used to laugh and call me names...gimpy etc. :rolleyes: They are lucky I didn't whack them and give them some sciatica to share!

mrsD 11-23-2009 02:49 PM

Low doses of Seroquel for what? Sleeping?

Antonia already mentioned here that she made a mistake typing that name--Seroquel. ( I think she meant Sinequan).

The truth about Seroquel is that Astra Zeneca has deceived physicians in the US about the safety of this drug. They reaped big bucks by hiding the diabetes risk, for years. This prompted
misleading information to doctors that this drug was "safer" than its competitors Risperdal and Zyprexa. And it is not. So many patients were switched to it, when the "truth" about the other two became common knowledge.

Small doses of this for sleeping...? Seroquel is going off patent soon, and their sales force is pushing this drug to internal medicine doctors for patients with "sleeping" trouble. This drug is an antipsychotic. I can remember small doses of Stelazine being pushed on OBGYNs for their menopausal patients to calm the nerves. This lead to huge side effects and damage to the dopamine system. Do doctors give patients in pain with sleeping problems a little bit of Haldol? Time has shown that both the older drugs like Haldol and the newer atypicals, are the SAME....No we don't see a little bit of Haldol, and we shouldn't be fooled into a little bit of Seroquel either! IMO.

Seroquel should remain for psychiatric use only, by trained professionals, who hopefully keep up with the negative studies that come out about the risks of this drug. It should not be used for situations that can be handled with drugs that have less risk.

http://www.medicalnewstoday.com/articles/142864.php

http://industry.bnet.com/pharma/1000...ctor-perfector

One can search Google and find tons of revealing information about how this drug was and is being marketed.

antonina 11-23-2009 07:56 PM

I just checked and the brand name for doxepin is sinequan, not seroquel.

Doxepin is great for sleeping...too bad the sx were so annoying.

I had sciatica for years and years. 36 years ago, during labor with my 2nd child, the disk @ L5, S1 splattered all over the nerve so I wound up having a laminectomy which worked beautifully. BUT, here's the crazy part: 3 yrs after surgery, sciatica reared its ugly head. A friend recommended I see Dr. John Sarno whose approach back then seemed radical. He believed sciatica was caused by the release of the same chemicals which produce migraines, asthma, etc. and not by any structural cause.

He cured me. I know when I feel sciatica coming on, it's because I'm ****** off at someone or something and I derail a full blown attack by remembering back to what or who set me off. He's written a few books on the subject and 36 years later, he's kind of a medical rock star.


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