Entacapone with Sinemet every time?
 

My Friend who had to stop Comtan because his tremor became so bad has now been asked to take 200mg of Comtan with each dose of 12.5/50 Sinemet (5-6 times a day).
Apparently he is supersensitive to Sinemet and therefore has problems with gait and the dystonia of the left toes is also apparently because of that - so he needs to make the most of his Sinemet. So the Entacapone.
I don't know what to think - here we are talking about a man who had trouble with 100mg A.M.+100mg P.M, and now he is being asked to take 200mg X 5/6 times.
Is this how Staleve works?
I am more than NERVOUS!
:eek: and double:eek:

I can understand your concern..What I know about Stalevo is that the body metabolizes some of the Sinemet before it reaches the brain, and the science behind Comtan is that Comtan blocks some of the receptors that cause the Sinemet to metabolize, so in theory it should allow the Sinemet to do a better job of treating symptoms rather than causing them, simply because more Sinemet completes its journey to the brain..I must say though, that 200 mgs of Comtan 5/6 times a day sounds like alot, but Im not a doctor, so I dont really know for sure..I take 600mgs of Sinemet, and 600 mgs of Stalevo daily, and it made a big difference in my quality of life

I had a tremor in my leg that was driving me bonkers, and the addition of Stalevo stopped it cold..but everyone reacts different to meds..What works for one peson, may not work for another, unfortunately