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-   -   Benzodiazaprine (https://www.neurotalk.org/peripheral-neuropathy/115912-benzodiazaprine.html)

Swmnupstrm 03-03-2010 04:13 PM

Benzodiazaprine
 
If I can just get really relaxed, like a glass of wine, symptoms lessen.

I don't want to rely on that, however - know it can aggravate pn.

Are benzodiazaprines any use in this condition????

mrsD 03-03-2010 06:51 PM

Benzos work in the short run, but in the long run, they are so habit forming and tolerance producing people get into a mess down the road.

They are GABA enhancers, and GABA is being looked at now in earnest for antidepressant activity. I believe some new drugs are in the pipeline for this.
http://en.wikipedia.org/wiki/Benzodiazepine

Benzos reduce nerve activity and also have some anticonvulsant actions. (anticonvulsants are also used to block pain).

Swmnupstrm 03-03-2010 06:57 PM

Hey, thanks. I have been on them before, years ago, for anxiety and panic. I had no trouble with dropping them - just am looking for something short term.

Methadone has not helped the pain.

Still in the process of letting the supplements do their work, getting more physically active, waiting for my orthotics, all that stuff.

cyclelops 03-03-2010 07:16 PM

I thought I had no trouble dropping them either....did it a dozen times. I was on them for sleep and restless leg. My advice is don't start. I am not on any now, thank goodness. They cause physical dependency, even if one is not emotionally attached. Try something else to get you to relax if at all possible. Benzos are not good. Xanax is not even allowed in the UK.


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