NeuroTalk Support Groups - Molecular Mechanism Triggering Parkinson's Disease Identified

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Molecular Mechanism Triggering Parkinson's Disease Identified

I don't usually get too excited about talk of a cure. I guess it's because we don't really know what causes PD, other than it has to do with decreasing dopamine. It is kind of hard to think about a cure when you don't even know the cause of the disease. I think this could be a big step in the right direction and I actually feel really hopeful that a cure might not be so far off in the distance.

Seems there exist medications to impact MicroRNA already.:

http://www.telegraph.co.uk/health/he...dentified.html
Genes that cause Parkinson's Disease Identified
By Richard Alleyne, Science Correspondent
Published: 6:20PM BST 28 Jul 2010

...Using the common fruit fly, researchers showed the gene variant results in
impaired activity of chemicals which fine-tune protein production in cells.

Prof Bingwei Lu, ..., said: "MicroRNA,...has been implicated
in cancer, cardiac dysfunction and faulty immune response...

... "Many pharmaceutical companies are already making compounds that act on these two proteins, which in previous studies have been shown to be associated with cancer.
"It may be possible to take these compounds off the shelf or quickly adapt them for use in non-cancer indications such as Parkinson's."...
Prof Lu said that testing on mammals could now begin.