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-   -   Best Fish OIl EPA/DHA ratio for Neuropathy (https://www.neurotalk.org/peripheral-neuropathy/136296-fish-oil-epa-dha-ratio-neuropathy.html)

aeb105 10-27-2010 04:35 PM

Best Fish OIl EPA/DHA ratio for Neuropathy
 
Anybody know the ratio for this? Is it more DHA or EPA in the fish oil that is better for us? Or should you just take a standard equal ratio pill.

mrsD 10-27-2010 05:36 PM

The EPA is the major anti-inflammatory part.

The DHA is more for the CNS and membrane integrity.

I think both are necessary.

Most fish oils have a natural ratio. There are some that were made for specific studies, example Bipolar, which have more EPA...OmegaBrite is one.

Some have more DHA, and that is targeting depression and
ADHD.

I'd say get the natural ratio. Both parts are valuable.

aeb105 10-27-2010 11:40 PM

Quote:

Originally Posted by mrsD (Post 709308)
The EPA is the major anti-inflammatory part.

The DHA is more for the CNS and membrane integrity.

I think both are necessary.

Most fish oils have a natural ratio. There are some that were made for specific studies, example Bipolar, which have more EPA...OmegaBrite is one.

Some have more DHA, and that is targeting depression and
ADHD.

I'd say get the natural ratio. Both parts are valuable.

Thanks, Mrs. D! That's what I have been doing since before I got Neuropathy. Taking the balanced ratio.

A couple times a year, I like to reevaluate all my supplements and optimize where I can. Any especially favored brands?

I am thinking of switching my Walmart-- Spring Valley, Fish Oil to Norwegian Gold Fish Oil from the health food store. Do you do 1 or 2 grams?

mrsD 10-28-2010 12:14 AM

Actually I switched to Krill oil last spring. And it seems to work well for me.

I use MegaRed. From what I read, the Krill oil works better at lower doses.

Dr. Weil's opinion:
http://www.drweil.com/drw/u/QAA40023...Krill-Oil.html

and another MD opinion:
http://www.proteinpower.com/drmike/u...why-krill-oil/

aeb105 10-28-2010 01:48 AM

Quote:

Originally Posted by mrsD (Post 709408)
Actually I switched to Krill oil last spring. And it seems to work well for me.

I use MegaRed. From what I read, the Krill oil works better at lower doses.

Dr. Weil's opinion:
http://www.drweil.com/drw/u/QAA40023...Krill-Oil.html

and another MD opinion:
http://www.proteinpower.com/drmike/u...why-krill-oil/

I had an intial reaction to Krill Oil last year when I tried it and let it slip. I had just ordered some more thru OrthoNutrition and will be giving this different brand a go.

Krill is also better than fish oil because of the powerful Astaxanthin antioxidant it contains as well as vitamin A and D. Not to mention the phospholipids.

I guess what I was looking at was ramping up DHA as I guess it is supposed to be helpful for the nervous.system. I was also thinking of myellin and the component of fish oil that regenerates it in people with MS. I would think that DHA would be the most valuable component for neuropathy as well. Norwegian gold markets an Crtical DHA: which sparked my curiousity and got me thinking.
http://www.renewlife.com/norwegian-g...tical-dha.html



Combining that DHA omega with ALCAR(acetyl-l-carnitine) or Huperzine A or other supplemental nerve growth factor stimulators might be helpful.

DHA with Epithelial Growth Factor Enhances Nerve Regeneration After Corneal Surgery
http://www.fatsoflife.com/article.ph...758&issueid=79

mrsD 10-28-2010 07:16 AM

You can ramp up DHA by taking extra. Take your regular oil so you get the EPA and then add DHA...

There is a Carlson's DHA 500mg which my son used.

But also you can buy DHA separately... it is not from fish, but is synthesized in vats. It is made by Martek in this country and there are several brands. Neuromins and Expecta are two.
Expecta targets pregnant women, but you can buy it and use it ;) .

I'd still take some EPA because it suppresses series 2 cytokines which are implicated in inflammation. Some nerve pain may be inflammatory in origin.

Sheltiemom18 10-28-2010 07:35 AM

The fish oil brand I've been taking is Natur's Bounty - almost out of it. There's no breakdown of EPA and DHA values on the label, only says 2 g, Omega-3 600 mg. So I have no clue if it's "balanced" or not. Thought all values had to be shown on the label?:Hum:

MrsD, do you buy the brand you use locally or on-line?

Thanks,

Sheltiemom

mrsD 10-28-2010 07:43 AM

I get the MegaRed at Costco. They just have a coupon going now for $5.00 off, so that puts it at about $12/90.

My husband uses their concentrated fish oil, by Kirkland.

I like the antioxidant in the krill oil.

I can't find yours online, Sheltiemom... there appear to be many.

Most fish oils will say omega-3 content, and break down EPA and DHA. The basic one is about 120- 150mg each, in a 1 gram cap.
But now there are concentrated ones, double and triple.
Typically EPA and DHA are similar in amount. EPA might be a bit more etc 20-50mg in a standard cap.

Many of the companies now have these concentrated versions.

I think one needs about 3 regular fish oils a day (or one triple), if they have some inflammatory problem. PN or arthritis or asthma, very dry skin, etc.

Sheltiemom18 10-28-2010 01:36 PM

Thanks, MrsD.

Been taking 3 fish oil a day per the rheumatologist for the Sjogren's and whatever else is might benefit.

When it's time to replenish the fish oil/Omega-3, will be sure to check out the EPA/DHA values and try to get a good brand.

boytos 10-31-2010 08:04 AM

hight dose of omega3 ***!

(Natural omega3 si safer than synthetic : see the last link)
The inclusion of omega-3 fish oils in the diet has been shown to help with autoimmune and inflammatory diseases (Kelley DS 2001; Simopoulos SP 1999, 2002) by suppressing synthesis of TNF-alpha (Endres S et al 1989). Vitamin E and fish oil work together to decrease pro-inflammatory cytokines, including IL-6 and TNF-alpha, in mice (Venkatraman JT et al 1999a,b). Omega-3 fish oils have been useful in patients with a variety of inflammatory diseases, including rheumatoid arthritis and atherosclerosis (Simopoulos SP 1999). Studies in humans with rheumatoid arthritis suggest that fish oil and vitamin E decrease inflammation in humans (Tidow-Kebritchi S et al 2001). Moreover, fish oil supplementation has shown anti-inflammatory effects, including decreased use of anti-inflammatory drugs, for patients with a variety of other chronic inflammatory diseases (Simopoulos SP 2002).

http://www.ncbi.nlm.nih.gov/pubmed/20090445
http://www.futureofmedicine.ca/images/Clin_J_Pain.pdf
http://www.fmnetnews.com/basics-news-omega110.php
http://en.wikipedia.org/wiki/Omega-3_fatty_acid#Fish

so 3g


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