NeuroTalk Support Groups - Local injection that give Long T relief

+ proof :)

Local injection inducing differentiation:

EPO :
http://www.doctorellis.com/Lecture.html

Progesterone because it works like EPO (induce differentiation) and is safe. Progesterone is on trial for carpal tunnel syndrome !

http://www.biomedcentral.com/content...-7221-5-11.pdf

And anti muscle fibrosis :

The muscle wound healing occurs in three overlapping phases: (1) degeneration and inflammation, (2) muscle regeneration, and (3) fibrosis
patients with traumatic TOS: type II fibers were atrophied; there was an increase in the average number of type I fibers (78% versus 53% in muscles from control patients); and there was a significant increase (mean: 36%) in connective tissue (muscles from control patients averaged less than 15%).
the changes in the anterior and middle scalene muscles are compatible with trauma, suggesting that fibrotic scalene muscles are an important cause of symptoms in traumatic & RSI TOS.

Hydrogel Delivery of Suramin
http://journals.lww.com/acsm-msse/Fu...Muscle.71.aspx

Myostatin agonist
http://www.jbc.org/content/283/28/19371.abstract
http://www.jbc.org/content/283/28/19371.full.pdf

Matrix metalloproteinase-1 enzyme
previous studies demonstrated that matrix metalloproteinase-1 (MMP-1) is able to digest fibrous scar tissue and improve muscle healing after injury
http://www.actabiomat.org/article/S1...085-8/abstract
http://www.scielo.br/scielo.php?pid=...rttext&tlng=en.
http://www.sciencedirect.com/science...f&searchtype=a
http://www.wipo.int/pctdb/en/wo.jsp?WO=1997014420

Decorin
Using decorin, an anti-fibrosis agent, to improve muscle recovery after injury ***(!?)
Our findings indicate that further improvement in the healing of muscle lacerations is attained histologically by the combined administration of IGF-1 to enhance muscle regeneration and decorin to reduce the formation of fibrosis.
http://onlinelibrary.wiley.com/doi/1...10436/abstract
http://www.sportsinjurybulletin.com/archive/decorin.htm
http://ajsm.highwire.org/content/29/4/394.abstract

And maybe, but more contreversial, oralSerrapeptase, supposed to get ride of muscle fibrosis as well.

Here a study for CTS with Serrapeptase (same problem as TOS but only on wrist)

This study was planned to assess the response of Serrapeptase in
patients with carpal tunnel syndrome (CTS) ====> Same mechanism as TOS !!

Twenty patients with CTS were evaluated clinically. After baseline
electrophysiological studies, these patients were given serrapetase10
mg twice daily with initial short course of nimesulide. Clinical and
electrophysiological reassessment was done after 6 weeks.

Mean age was 43.9 years with male to female ratio of 1:2.33. Sixty
five percent cases showed significant clinical (13/20) improvement which
was supported by significant improvement in electrophysiological
parameters. Recurrence was reported in only four cases. No significant
side effect was observed. ===== > 9/20 were saved with no reccurence and the 4 case can try again + very rare side effect not like surgery !!

CONCLUSIONS: Serrapeptase™ therapy may proved to be a
useful alternative mode of conservative treatment. Larger study
may be further helpful to establish the role of Serrapeptas in CTS. Don't know how but it work !

http://www.ncbi.nlm.nih.gov/pubmed/11225219
http://neurotalk.psychcentral.com/thread135530.html