Prolactin & Myelin
 

Had my neuro scribe me sleep med for round of steroids. Gave me Rozerem. Reading mfr's site, I came accross the 1st line below. Looked up the rest...

Rozerem has been associated with decreased testosterone levels and increased Prolactin levels. (Takeda Pharmaceuticals )

Prolactin has many effects including regulating lactation and stimulating proliferation of Oligodendrocyte precursor cells. (Wiki)

Oligodendrocyte precursor cells in nervous tissue cells precede oligodendrocytes, and may also be able to generate neurons and astrocytes. The principle function of oligodendrocytes is to provide support to axons and to produce the Myelin sheath, which insulates and lowers the effective capacitance of axons. Myelin is 80% lipid and 20% protein and speeds the conduction of action potentials down the axon. Oligodendrocytes, unlike Schwann cells of the PNS, form segments of myelin sheaths of numerous neurons at once. The processes of a given oligodendrocyte wrap themselves around portions of the surrounding axons. As each process wraps itself around, it forms layers of myelin. Each process thus becomes a segment of the axon's myelin sheath. (Wiki)

COULD THIS BE ONE OF THE PREGNANCY REMISSION COMPONENTS? (EddieF)
Are they saying Oligodendrocytes ARE the precursor or require? (EddieF)

Well of course it's not covered by my ins. Sheesh. $200 as written. Pharmacist said the 3 given to me by ins co are different class.

Eddie, my answer would have been no.

Prolactin occurs more in the middle of pregnancy, and the nature of it is to provide a good source of food for a baby. It helps the baby's brain develop in the womb, as it is growing, not the person who takes it for sleep aid.

What protects women during pregnancy is EPF (Early pregnancy Factor). That does turn down the the "T", and increase Estrogen and Progesterone.

After pregnancy they get lowered and then a relapse may occur from the drop in Estrogen, which btw, is being tested in clinical trial and MS now, but along with "C" so it will be hard to decipher the outcome.

Are you in a relapse, why the steroids? Did I miss something?

I thought Test went up hence increased hair growth during pregnancy. I know mine grows like weeds on Test.

Yes my MS has been progressing rapidly the past few months :( I started 2 months ago what's in that trial but i'm on Ty not C. It's not helping but i'm taking only 4mg estriol not 8 & 4mg progesterone. I do 1/2 C shots now and then as well. The last C shot stopped spasms in my left thumb/index finger the next day. Haven't returned since. If i lose much more feeling in my left hand (right is far worse), life will be hard...maybe too hard. I upped my fishoil to 4800mg/day and bying CoQ10 next time I get to store. Dr Oz says it increases oxygen and people over 50 (im 40's) swear by it.

Lady your upcoming procedure is keeping me hopefull! :)

I'm right!
 

http://www.news-medical.net/news/2007/02/20/22065.aspx !!!

Years ago i started this thread.
I stopped estriol & progesterone many many yrs ago.
Took it for 1yr. Possibly 4mg of each.
Price tripled after 1yr so i quit it.

Progesterone helped trumatic brain injury on tv news many years ago.
Anyone know anyone that tried & outcome?

Anyone try Glutamine for sickle cell? I saw that worked well on tv too.
Again, many years ago.

A Phase 3 clinical trial looking at the effects of L-glutamine treatment on the consequences of sickle cell disease has been reported.

https://www.nejm.org/doi/full/10.1056/NEJMoa1715971

Eddie, I posted about HGH in many severe health conditions here.

https://www.neurotalk.org/multiple-s...f1-hgh-ms.html

My daughter 56 and myself 81 both use the homeopathic gel and then I did a lot of research on HGH working to reduce/reverse a lot of issues we deal with.

Thanks caroline & kiwi.
Last night i meant to post estriol in a estriol thread not this one lol but so be it.

I've asked a few docs over the years for hgh to keep & use in cycles when my wrists get injured (i'm a c7 complete para) because weak wrists equals death to guy like me. I have no doubt it helps caroline. It's not just for movie stars.

Kiwi a nurse friend of mine has daughter with sickle cell & i saw it on tv news almost 10yrs ago with great results in 1 guy that has it.

Estriol & progesterone 4mg each i believe i took, made at compounding pharmacy. I might give it a go again. On tysabri for 10yrs, thinking about Ocrevus.