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-   -   looking back at the first drugs I used by RX for nausea from Sinmet- Domperidone! (https://www.neurotalk.org/parkinson-s-disease/140810-looking-drugs-rx-nausea-sinmet-domperidone.html)

lou_lou 12-14-2010 06:28 PM

looking back at the first drugs I used by RX for nausea from Sinmet- Domperidone!
 
Gastrointestinal problems
There is some evidence that domperidone has antiemetic activity.[2] Domperidone is used, together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) in the treatment of nausea and vomiting.

Domperidone is a first choice antiemetic in most countries.[citation needed] However, it is not approved for prescription in the US. Although it has never been officially approved for use in the United States, domperidone is sometimes purchased from pharmacies in other countries for this purpose.

It can be used in patients with Parkinson's disease[3] because, unlike metoclopramide[4], domperidone does not cross the blood-brain barrier.

Domperidone has also been found effective in the treatment of gastroparesis,[5] a stomach motility condition, and for paediatric gastroesophageal reflux (infant vomiting).

[edit] Lactation
http://en.wikipedia.org/wiki/Domperidone


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