Unearthing a pathway to brain damage
Neuroscientists have long suspected that abnormal calcium signaling and accumulation of misfolded proteins cause an intracellular membrane-bound organelle called the endoplasmic reticulum (ER) to trigger the abnormal death of cells implicated in many neurodegenerative diseases. However, the underlying mechanisms have proved elusive.
ACS Chem Neuro Free Issue - Peer-reviewed journal on molecular mechanisms in Neuroscience - pubs.acs.org/acscn http://www.physorg.com/news/2011-02-...way-brain.html |
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