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-   -   Fumarates and MS: very interesting! (https://www.neurotalk.org/multiple-sclerosis/146245-fumarates-ms.html)

mrsD 03-08-2011 06:20 AM

Fumarates and MS: very interesting!
 
Here is a new article from our Health News forum today:

http://www.eurekalert.org/pub_releas...-pmr030711.php

There is a fumarate salt OTC:

Carnitine fumarate from Epic4health.com
example:
http://www.epic4health.com/catirelfu560.html

This is the same formula as Carnitor RX

Carnitine is used sometimes for PN. Also some drugs like Depakote deplete it so those patients benefit from the supplement. And there are genetic errors of carnitine synthesis in the body.

The fumarate information is interesting...so I will post this on our PN board too, today.

here is a 2010 link to fumarates in psoriasis treatment:
http://www.ncbi.nlm.nih.gov/pubmed/21175564

What is fumarate?
http://en.wikipedia.org/wiki/Fumaric_acid

Kitty 03-08-2011 11:06 AM

I wonder if it's only a successful supplement if you combine it with an interferon med? Would it serve any purpose by itself? I'll be interested in hearing about the study results this summer.

[An international, placebo-controlled, blind study (DEFINE, Sponsor: BiogenIdec) with 1,200 MS patients and the fumaric acid salt BG12 has just been completed under the leadership of Prof. Gold. Evaluation is being expected for summer 2011. "If the study is successful, one could easily imagine that the antioxidant effect of the fumaric acid also synergizes with established MS medication such as interferon-ß thus forming an ideal combination therapy", Prof. Gold speculates. "This is significant insofar as both fumarates as well as interferon do not contain any long-term risks according to the current state of knowledge – unlike many modern strong MS therapies."]

Debbie D 03-08-2011 02:50 PM

Wish the docs had known about this when my dad was alive...he had bad psoriasis...


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