Mobic vs Celebrex or Ibuprofen
 

Hi everybody. My husband has many health conditions. Reactive arthrits being one. In your opinion whch one of these anti- inflammatory's drugs (Mobic, Celebrex or Ibuprofen )are most effective, yet having the least side effects.

Due to a couple stomach ulcers his doctors told him to avoid Ibruprofen. Yet after a month he doesnt seem to feel mobic helps.

IS Celebrex much better?

Thank You

I've been waiting for some other responses.... I can't take ibuprofen either, so my doc prescribed meloxicam (Mobic) because it's inexpensive. I'm not pain-free, but I think it helps some, especially on the bad days.

Doc

All three can cause stomach ulceration.

Mobic and Ibuprofen are not Cox-2 specialists.

Celebrex mainly works on Cox-2 (inflammation) but has some weak Cox-1 effects (stomach ulcer potential).

Mobic is chemically related to piroxicam (which was one of the more toxic NSAIDs.) Its brand name was Feldene. It fell into disfavor because of the severe reactions some people had to it.

Some doctors remain confused about Mobic thinking it is like the Cox-2 inhibitors, because it came out at the same time period.
But it is NOT sparing of the stomach potential for ulcers, and it has the same cardiovascular warnings with it.

All the NSAIDs have potential for causing heart attacks, because they block a beneficial Cox-2 cytokine called prostacyclin. The one less dangerous to the heart is naproxen (OTC Aleve). I use the Aleve liquigels now when I need some pain relief, and I have found the liquigel form very fast acting and stronger than the pills. I think you can get by with much less with them. Only one a day will last me all day and work on mild to moderate pain for me.

I use Salonpas patches more often than I take pills. They work on my pain issues locally and are safer.

Using a quality antioxidant like grapeseed extract (200mg a day) can really help with chronic arthritis and allergies I have found.

What are Salonpas patches, please. I used some patches that were a topical anesthetic a few years ago that someone gave me. I can't remember the name-- :Bang-Head: it's a very common one. Anyway, I got some relief. I would be very interested in the topicals.

Salonpas are over the counter... and one new stronger one has even been approved by the FDA (a rare event for an OTC product)

http://www.salonpas.us/other-products/salonpas

I use the ones with methyl salicylate in them. (they make other types with only menthol)... so read the labels.

I also use Biofreeze gel for my feet, hands and knees. This is over the counter too. My physical therapist when I was in rehab introduced me to it.

Thank you for a very timely post for many. Due to an aortic valve replacement, my hubby has had to give up his beloved ibuprophen. He took 10 on an average day but now it's Tylenol and Tramadol. He was a farrier for about 30 yrs. He also used DMSO, with good results, he said. He wants me to use it on my back, etc. It can really burn, though. :eek: I may start with a small amt. and go from there. He can get it at the racetrack, rather than a health store, where it is much more expensive. They have used it for years on racehorses. FYI, TENS units have also been used on horses for a long time. I'm using hubby's when I think about it. The unit is expensive. He got his free from the VA, where he gets excllent care. :Tip-Hat: I wish I had his health care! I'm waiting tp get medicare in two years. Free clinic for me till then. It's better than no health care at all and I am grateful for it.

Anyway, I was on Celebrex for a while, but the free clinic gives naprosyn. I have never been able to tolerate aspirin or ibuprogen because of hx of duodenal ulcer and chronic gastritis. The naprosyn seems okay, though.
I've never used Mobic or given it to a pt. I would like to know what it is. Is it new?

I wish I could be more helpful. :Dunno: I'm sure you'll get some good help here, though. :grouphug:

No, it's available generically as meloxicam. 15 mg, once per day.

Naproxen still has side effects (as do all drugs). My stomach can't tolerate it either (IBS), and it gives us both tinnitus worse than aspirin, but I do fine on meloxicam.
Google: naproxen side effects

TENS units are not that expensive anymore (<$100). They can be purchesed without prescription, but a prescription is usually required for insurance reimbursement.

Doc

Anti-inflam
 

Try to avoid all of them, as they carry quite considerable health risks, and long term usage is not fully understood as yet. Don't be part of the long-term trial!
I've stopped them entirely, having tried voltaren, feldene, celebrex and mobic.
Always hard to say if there was any benefit as I still had to take pain meds at the same time.
Try to stick with non-addictive pain meds, such as paracetamol.
I'm having great success taking 2x 665mg caps every 8 hours, with an occasional tramadol if I overdo it.

But-----the biggest benefit I've had with my 30 years or so of chronic pain is simply from large daily doses of magnesium oil.
Been on it a year and still improving. Muscle pain virtually stopped, so now just have to treat a few joint pains.

Try to avoid the dosage increasing medication path like I was on. It seems that the actual mediction was causing a lot of the pain, oddly enough.
Once I was off it, the pain lessened dramatically.
Keep an open mind and keep researching!

Generic mobic did almost nothing for me, and I need the high dose Mobic to help. BUT, I have also been warned that in the long run, NSAIDS destroy our joints due to their action of inhibiting blood vessel formation (which may make them helpful for some cancers).

Thanks to all for responding. But isnt paracetamol the same as Tylenol? I thought that caused liver damage when taken for years?

Keep the suggestions coming please.

Thanks!!!!

Diclofenac
 

I have tried most of the meds listed in the previous posts. Right now I am not taking anything due to the ACDF surgery. I was taking Diclofenac 75 mg 1 tab 3x a day as an anti inflammatory. It seemed to help me more than the other meds. Wish I could start taking it again, but it prohibits bone growth. I need to wait until I am at least at the 6 month mark or there is a fair amount of bone growth.

**************************************** ********** **
12/9/2010 ACDF C5-6 C6-7 with plate, screws,
BMP & bone fragment filled cages
2/14/2011 trying to go back to work as a teacher
2/17/2011 starting PT
wearing bone stimulator 4 hours a day
DDD, arthritis, herniated disks, pinched nerves
3 months saw a little bit of bone growth (YEAH)
4/15/2011 Home Tens Unit

Paracetamol
 

My GP says it is the safest pain med to use.
Like any drug, overdosing can cause problems.

Found this in Pharmweb, and is typical of other entries that I found.

Q:If paracetamol products are used long term, is there a risk of liver damage?
A :Many people use paracetamol for extended periods under supervision of their GP. There is no evidence to show that, at recommended dosages, paracetamol causes liver injury when used for long periods (4).

I have many intolerance's so my issue may be different than others. Meloxicam made me very ill..caused panic/anxiety attacks, severe pain just under my ribs, vomiting, and I even passed out. I stopped the med that day and this was only 4 days into using it. I was sick every 2 or 3 days for 2 to 3 weeks afterwards and am just beginning to get over it. My rheumy still wants me to try other meds and I refused. I had to go back on Celexa for the panic, I just can't seem to overcome them now. I, like Mrs. D do ok with Aleve and told him I will use it.

I was recently diagnosed with fibromyalgia and osteo arthritis.

Yes, and from what I've read, your dosage is pretty high. It's within limits for short-term daily use, but high (1330 mg) for single dose - 1000 mg. is the recommended maximum within a 6 hr. period. (Yes, I see it works out proportionally) For long-term use (longer than 2 weeks), the recommended maximum is now 2600 mg./day (which comes out to 2 - 325 mg tabs every 6 hrs.).

Something to look into is the supplement NAC (N-acetyl cystiene). It's what hospital ERs give patients for tylenol (acetaminophen/paracetamol) toxicity/overdose. Taken daily, it may reduce/avoid potential liver damage from paracetamol.
See: http://yarchive.net/med/tylenol.html

I've been taking acetaminophen/paracetamol with NAC for many years now. I just had my liver tested again this past week and it is well within normal.

Magnesium Oil
 

I am very interested in the magnesium oil. What is it and how do you take it? What quantities do you find give you relief? I have chronic sciatic pain and would like to find something that works for relieving it other than Anti-Inflammatories.

Magnesium oil
 

I use magnesium chloride, which is just concentrated seawater, rich in minerals. This is the one I use. In Australia, it is not allowed to be sold for internal use (just hasn't been looked at), but elsewhere it is.
http://www.echolife.com.au/products/...esium-oil.html

This is a good site to read about the benefits from a doctor's viewpoint.
http://drcarolyndean.com/2010/09/mag...e-for-muscles/

I take 1-2 teaspoons of it diluted in about 600 ml of water, which I then drink throughout the day. Best to drink it in small amounts to avoid upsetting the gut.
I found relief after just a week, and haven't looked back. It's the only thing that has given me relief from sore muscles.

You can also get a powder form, which you mix with water. It is a bit weaker so slower to work, but still OK.
The tablets are useless as they are too weak and you can't take higher doses. With the liquid one you can, and you know when to back off when you get loose bowels!
Definitely worth a try. This is a cure for muscle problems, and not just a treatment.
It may not stop the sciatic pain, but should certainly help with tight muscles which can be very painful as well, and which you probably have as you try to cope.

Magnesium Oil or Gel
 

Magnesium Oil is Magnesium Chloride and water. When mixed the solution feels like an oil but is not. It is transdermal which means enters the body through the skin. Magnesium oil or Magnesium gel is great for pain and also for increasing magnesium in the body.

Magnesium Oil can often feel sticky or sting a little.My husband has had great success with Magnesium Gel Forte from an Australian company.

This gel is more like a body lotion to use and is great for the ladies too.

Biofreeze
 

Try the Biofreeze spray. Its much stronger than the gel. I have found that it works well for my knee pain.

Best of luck!

Magnesium
 

I've changed to ReMag Solution. Just 4 drops under the tongue twice a day.

Nice and easy, and it works much more effectively as it gets straight into your system without going through the gut or skin.

Will buffered magnesium glycinate 1.5 grams work as well as reMag.

I have frozen shoulder and trying not to take Mobic, as I have heard all sorts of horror stories about it.
TIA

I didn't know Mobic and Feldene are one in the same. Feldene put me in the ER with a stomach ulcer back in the 80's. My back was doing great but my stomach was not. I knew so little back then on all the side effects etc of the drugs.

Today with advancing OA and a hip replacement mess, I use Ibuprofen, 4 per day and Pain RX herbal supplement for in between the ibuprofen. So far so good and have to thank DGL for keeping my stomach safe.

A few years ago I got a script of meloxicam and had no clue it's related to Feldene. I couldn't take it and forget why...maybe it did nothing or maybe it constipated me....so what I do is crush a couple tabs and add it to some of my topicals and use a toothbrush to rub on some topicals where I can't reach.

I know OA is worse and if I really have this FM it's added to the misery.

baba222, hope you can get that shoulder unfrozen. I posted what my chiro said about that. Can't say about the mag exchange, I take different mags and glycinate is one of them. C