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-   -   A piece of the puzzle in the causation story (https://www.neurotalk.org/parkinson-s-disease/156988-piece-puzzle-causation-story.html)

Muireann 09-11-2011 06:35 AM

A piece of the puzzle in the causation story
 
http://www.prweb.com/releases/2011/9/prweb8773480.htm

ladybird 09-11-2011 09:32 AM

That's exciting! Thanks for that. There seem to be breakthroughs in understanding in quite a few fields of study. They will get there!

johnt 09-11-2011 08:30 PM

Thanks for starting this thread.

The paper can be found at:
http://www.pagepress.org/journals/in...ni.2011.e7/pdf

"Parkinson's disease: an inquiry into the etiology and treatment"
Jannetta P. J., et al
Neurology International, Vol 3, No 2 (2011)

"[The] midbrain was decompressed by mobilizing
and repositioning the posterior cerebral artery
The patient's Parkinson's signs disappeared
over a 48-hour period. They returned 18 months
later with contralateral peduncle compression."

"MRI scans in 20 Parkinson's patients and 20 age and sex
matched controls were evaluated in blinded fashion
... showed that 73.7 percent of
Parkinson's Disease patients had visible arterial
compression of the cerebral peduncle. This was
seen in only 10 percent of control patients (two
patients, one of whom subsequently developed
Parkinson’s Disease)".

This paper is worth a read. Early days, but note those words "etiology" and "treatment".

John

lindylanka 09-11-2011 09:08 PM

Feel like I keep banging away at this, but the sooner they start defining the differences the better, this is another keeper I think. A few years ago there was a lot of talk of normal pressure hydrocephalus and Chiari malformations. I wonder whether those got disseminated into the wider neurology community or not. I seem to remember reading also about a different type of arterial study in which there was a twist that affected blood flow? and caused PD like symptoms....... I am never sure whether these kind of findings get followed through, or whether they get overtaken by the next thing........

But this is a very interesting piece of work.

moondaughter 09-12-2011 11:25 AM

beware adrenaline shots by your dentist
 
Quote:

Originally Posted by Muireann (Post 804375)


interesting...perhaps this gives a deeper perspective for the sometimes positive effects of using TMJ "appliances" and specialized upper cervical chiropractic treatment (such as NUCCA), exercise, meditation etc for movement disorders for the simple reason these venues improve circulation. (c'mooooooooooooon oxygen!!!)
Thanks for the post and btw....the pd tremor started (age 36 ) when i was sitting in the dentist chair after receiving 12th carp(within 4 days) of prilocaine and epinephrine (anaesthetic) to my lower jaw ...could the shot have collapsed my trigeminal nerve? I always wondered if the dentist missed the subcutaneous target....btw i have the dentist use nonadrenaline anesthetic shots now (such as carbocaine)....and very small doses.
md

Muireann 09-13-2011 11:48 AM

The actual paper itself is well worth a read, particularly the discussion section, for the rather humble admission that klutzy use of the power saw, scalpel and scissors in autopsies is violating the integrity of the vascular structures whose state of functionality needs to be described. The guys doing autopsies need to approach their work more from the stance of archaeologists, with a bit more respect for forensics.


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