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"Epidemiology and etiology of Parkinson’s disease: a review of the evidence"
"Epidemiology and etiology of Parkinson’s disease: a review of the evidence"
Karin Wirdefeldt • Hans-Olov Adami • Philip Cole • Dimitrios Trichopoulos • Jack Mandel Eur J epidemiol (2011) 26:S1-S58 http://www5.ocn.ne.jp/~ajca/cosic23.6-17.pdf The above paper is a massive (more than 50 pages and 600 references) review of the state of play. Highlights: A table showing the distinctive clinical features of different gene types (e.g. those with PARK2 on average have a slow progression). "Higher serum uric acid concentration has been linked also to slower clinical progression of PD" John |
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