An interesting link to a testominal thread about the use of Benfotiamine
 

I am normally very dubious about testimonials of any kind, but the following link will take you to a thread of testimonials that are striking regarding the use of Benfotiamine for neuropathy and a host of other things:


http://benfotiamine.org/testimonials.htm#case1


What do you think of this feedback ... legitimate, bogus, or somewhere in between? These seem to be real people getting real results!

Well, I am always dubious... what strikes me at the link you provided today, is the dose recommended! They are all very high.

When you need more input use our PubMed link in the upper right of the page. When you get there type in a good keyword like this:
benfotiamine neuropathy

I did this just now and found:
http://www.ncbi.nlm.nih.gov/pubmed/20188835

This study does give doses:
http://www.ncbi.nlm.nih.gov/pubmed/18473286
And does reiterate what I post that it takes TIME to show benefits. People often push the dose UP to get faster response IMO.

This is a chemical explanation:
http://www.ncbi.nlm.nih.gov/pubmed/18384109

http://www.ncbi.nlm.nih.gov/pubmed/18220605
Before gabapentin and SSRIs drugs, thiamine was the main treatment for PN. I believe it should remain high on the list for
any PNer and benfotiamine is superior IMO. However, benfotiamine at one time was super expensive and few could afford it. That has changed in the last 3 yrs or so.
Thiamine remains inexpensive, but it makes some people have a body odor that limits its use.

This PDF gives some good data:
http://www.altmedrev.com/publications/11/3/238.pdf

This is an older paper:
http://www.ncbi.nlm.nih.gov/pubmed/16359659

This is from 1999:
http://www.ncbi.nlm.nih.gov/pubmed/10219465

I used to use thiamine in bursts. A month or two at a time, in the past. When Benfotiamine became affordable, I changed to it.
I only use 150mg a day now, but I started at 300mg in the beginning. I don't feel it is a cure...but it sure does prevent progression, and take care of alot of the discomfort for me.
I do think some people have a higher genetic requirement for it.

This one from 1996: Germany where the beginning studies originate.
http://www.ncbi.nlm.nih.gov/pubmed/8886748

Ms D:

I was impressed by both the sincereity of the posts and the fact that they seemed to placed by real and identifiable people.

I began taking it four days ago at 150 mg / day and then last night went to 600 mg per day.

I am also taking it in conjunction with 200 mg of R-Lipoic Acid (split AM and PM) per day.

Thoughts?

Well, benfotiamine does not have risky high dose postings anywhere I could find. Because this is fat soluble, it may be that you reach a steady state with it over time, so that systems may be saturated and not need so high a dose.

If you have the funds to pay for it then give it a try.
Regular thiamine is eliminated quickly (within 4 hrs ) thru the urine. The benfotiamine form lasts longer in the body.

Notice that there are not many recent posts on that link.
And all the early ones used 600mg, or more, but then that fact
no longer appears in the later posts.

Something so miraculous that it can cure TN, sciatica etc, would be picked up by doctors rather quickly. Yet benfotiamine remains in the diabetic neuropathy world instead.

I have no doubt that it is very useful... but I don't think it will work for everyone that same way. I think it will work best in people with errors in thiamine metabolism mostly. You will see if there are any benefits within the first month or two.

Carpal Tunnel
 

I found a link on Neuro Talk regarding Carpal Tunnel Syndrome and Benfotiamine. My hub started on 150 BID, and the Carpal Tunnel disappeared. I used to have to pack his wrists in ice nightly - since Benfotiamine, no need. At this writing, he is symptom free.