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-   -   Australian scientists discover key to halt nerve fibre damage in MS (https://www.neurotalk.org/multiple-sclerosis/168845-australian-scientists-discover-key-halt-nerve-fibre-damage-ms.html)

Koala77 04-27-2012 02:31 AM

Australian scientists discover key to halt nerve fibre damage in MS
 
Scientists from RMIT and Monash Universities announced today a discovery that shows blocking a specific protein may have the ability to act as ‘hand brake’ to the progression of the disease in people with Multiple sclerosis (MS).

http://www.msra.org.au/australian-sc...ibre-damage-ms

mrsD 04-27-2012 06:19 AM

They are certainly "mum" about the identity of this drug...which is already on the market.

I'm still searching for it. Finding other articles, but still no details.

SallyC 04-27-2012 11:34 AM

Thanks Annie, yes what is it??:)

mrsD 04-27-2012 11:54 AM

I finally gave up on looking this morning. I searched all the papers on PubMed by this guy.. Petratos S

The "approved" drug is not mentioned anywhere I could see.

missj 04-27-2012 02:07 PM

My guess is that its a drug for HIV

SallyC 04-27-2012 02:10 PM

It may be Lacosamide (LCM)....it blocks the crmp-2 protein (found in MS lesions) in epolepsy?

Read this http://www.ncbi.nlm.nih.gov/pubmed/22433297

mochagirl13 04-27-2012 04:22 PM

I couldn't find it either. I'll ask the neuro who is a MS specialist at new hospital I'm trying. Couldn't get appt. until 5/25. The hospital is a teaching hospital with a neuro clinic.

mrsD 04-27-2012 04:49 PM

Lacosamide=Vimpat:

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000506/

In the study which Sally found, it was injected directly into the brains of the animals.

I wonder if this will ultimately end up helping TBI patients too?

Good work Sal! ;)

EddieF 04-27-2012 06:14 PM

Progesterone helped TBI...a lot. Back to MS. Hope you's track the compound down!

Mariel 04-30-2012 11:46 AM

It sure would be nice to know. I suppose the drug companies must profit from this and thus make it secret until it's patented. Sounds like an important discovery!


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