NeuroTalk Support Groups - decompression for Chemotherapy induced Neuropathy

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decompression for Chemotherapy induced Neuropathy

Anyone had this nerve decompression surgery for chemotherapy induced neuropathy?? They are trying to extrapolate the diabetic population to the chemotherapy induced neuropathy.

Nerve decompression for chemotherapy induced neuropathy

Anyone had the nerve decompression surgery for chemotherapy induced neuropathy?

Before having an invasive procedure...I'd try using some
acetyl carnitine... Start at 500mg a day, and increase to 2000mg if necessary, weekly. It might help support the damaged mitochondria. There are studies on PubMed showing this is helpful. There are several papers on PubMed like this one:
http://www.ncbi.nlm.nih.gov/pubmed/22271810
use keyword "acetyl carnitine chemotherapy"

I don't see how "compression" is happening. Chemo damages
mitochondria in nerves, but I don't see it causing a compression.
Hypothyroidism will compress because it deposits a tissue there along the nerves and ligaments.

What does low thyroid do to the nerves with the tissue? That is interesting. I am taking Thyroid.

The body makes this surplus tissue with the low thyroid....and that then compresses tight spots around some ligaments.

http://www.townsendletter.com/Dec200...hyroid1208.htm

Quote:

Myxedema, which is the retention of mucin, can also occur when the tissues do not properly process and utilize thyroid hormone. (Myx is the Greek word for "mucin," and edema means "swelling.") Mucin is a compound comprised of sugars bound to a protein and in modest amounts is a constituent of connective tissue. (Connective tissue lines blood vessels, comprises nerve sheaths, is part of the fascial envelope surrounding muscles, and is in organs and glands, in the gastrointestinal and urinary tracts, and in the mucous membrane lining of the respiratory tract, including the sinuses.) By nature, jelly-like mucin absorbs water. When present in normal amounts, mucin is not a problem. But in excess, the hydrophilic (water-loving) mucin can cause serious problems wherever it accumulates in the connective tissue. Over half of the hypothyroid population (55%-60%) has abnormally high amounts of mucin, which accumulate more with age. In fact, the medical term for "hypothyroidism" used to be myxedema.

This leads to carpal tunnel and tarsal tunnel.

Thank you. So I guess getting the thyroid at a good level will stop that or reverse it? That might have helped me along with the other things I do.

Does this happen all over the body? Or small areas like Carpal Tunnel?

I am not sure. The article says it only happens in some patients.
I was one of them.

Quote:

Originally Posted by Sallysblooms (Post 910955)

Thanks for the response. Some of the more recent studies I've seen also showed mixed reviews with ALCA, some with worsening of neuropathy.

I am 7 years post chemo. My right foot and leg feel normal. My left foot, ESP heel, still have moderate neuropathy. I have tried some of the supplements recently, b vitamins, alpha lipoic acid, glut amine, ALCA and find that they seem to make it worst. Not sure what to make of it--- true worsening vs regeneration if possible.

Thanks