NeuroTalk Support Groups

NeuroTalk Support Groups (https://www.neurotalk.org/)
-   Myasthenia Gravis (https://www.neurotalk.org/myasthenia-gravis/)
-   -   There is future hope (https://www.neurotalk.org/myasthenia-gravis/177483-future-hope.html)

pingpongman 10-04-2012 04:07 PM

There is future hope
 
http://www.labspaces.net/124017/Rese...gravis_in_mice

StephC 10-04-2012 08:50 PM

I read about this on another forum but i got the impression that this was actually old news? Not sure but i thought someone on that forum said the same thing had been done about 8 years ago in UK and when i re-read the john hopkins release I dont see where they actually say this is New discovery or when it was. Corrections welcomed if i misread please say so.

southblues 10-04-2012 09:22 PM

Does anybody have a link to the actual scientific publication?

AnnieB3 10-04-2012 10:17 PM

Thanks, Mike. You may not like to know the following info because it means that this work has hit road blocks before, due to egos, funding and the FDA. ;)

The first one is the Drachman study. This work rides on the shoulders of the targeted chemotherapy research done in the past several years. Alice could tell you about that.

http://www.ncbi.nlm.nih.gov/pubmed/22769060

And I'm sure a lot of you are familiar with the work of Dr. Blalock in regards to attempting to get a vaccine for MG. There's been a "block" of his work, I believe due to the fact that the big guys (like JH and MC) wanted to come up with something better so they could get the credit.

http://www.ncbi.nlm.nih.gov/pubmed/21861992

Here's some history on that.

http://www.uab.edu/medicine/neurobio...ty/66-eblalock

http://online.wsj.com/article/SB1000...342139200.html

These are relatively related.

http://www.ncbi.nlm.nih.gov/pubmed/22981737

http://www.ncbi.nlm.nih.gov/pubmed/22941261

http://www.ncbi.nlm.nih.gov/pubmed/22952904

http://www.ncbi.nlm.nih.gov/pubmed/22689047

http://www.ncbi.nlm.nih.gov/pubmed/22642809

http://www.ncbi.nlm.nih.gov/pubmed/22626443

And this is for you MuSK patients.

http://www.ncbi.nlm.nih.gov/pubmed/22396395

And what they're working on to help determine severity of MG. As if we can't figure that out without a study! ;)

http://www.ncbi.nlm.nih.gov/pubmed/21861992

alice md 10-05-2012 04:29 AM

It's quite simple.

All you have to do is turn into a mouse. :catalan2:

(or if you have MuSK MG you can turn into a Musk Rat).

And then not only will you be cured of MG, but of many other diseases.


As I said elsewhere, the gap between preclinical studies and clinical trials in MG is enormous and incomparable to any other disease that I know.

AnnieB3 10-05-2012 10:51 AM

Too funny, Alice. And what I find really funny is that MG is a progressive and debilitating disease when they want money for their research but it's a well-understood disease and easy to live a normal life with when they're discouraging us from getting social security disability.

singergal64 10-05-2012 10:58 AM

Quote:

Originally Posted by pingpongman (Post 919737)

Thank you for sharing this article! It does give us hope and all others who suffer from autoimmune diseases!:)

alice md 10-05-2012 11:06 AM

Quote:

Originally Posted by AnnieB3 (Post 920008)
Too funny, Alice. And what I find really funny is that MG is a progressive and debilitating disease when they want money for their research but it's a well-understood disease and easy to live a normal life with when they're discouraging us from getting social security disability.

Yes, I noticed the same.

It makes you reach the inevitable and only possible logical conclusion- this is a very debilitating disease in mice (and hence justifies all this mouse research), whereas in humans it is a very well understood disease and easy to live a normal life with.

so, maybe (since our illness is quite debilitating) we are mice and just don't know it? ( I mean if we can be in "remission" without knowing it, everything is possible).

I will go take a look in the mirror . Maybe there is hope for us then...

AnnieB3 10-05-2012 11:10 AM

I really do miss eating cheese.

jana 10-05-2012 01:57 PM

Quote:

Originally Posted by AnnieB3 (Post 920008)
And what I find really funny is that MG is a progressive and debilitating disease when they want money for their research but it's a well-understood disease and easy to live a normal life with when they're discouraging us from getting social security disability.

I think this needs to be put on T-Shirts -- and on coffee cups -- and on posters -- and on.......

Oh my GOODNESS!! The BRILLIANCE of this statement is just making my head spin. Really!!


All times are GMT -5. The time now is 09:23 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.