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-   -   Low dose Naltrexone (https://www.neurotalk.org/peripheral-neuropathy/177487-low-dose-naltrexone.html)

Steven N 10-04-2012 05:10 PM

Low dose Naltrexone
 
I just read about Low Dose Naltrexone. Does anyone here have experience with it? I know it's used for MS; is it also good for PN?
Thanks,
Steven

bent98 10-11-2012 04:43 PM

Quote:

Originally Posted by Steven N (Post 919751)
I just read about Low Dose Naltrexone. Does anyone here have experience with it? I know it's used for MS; is it also good for PN?
Thanks,
Steven

http://painsandiego.com/2011/01/

This explains about glia cells


http://painsandiego.com/tag/allodynia/


Naltrexone is an immune modulator.

The site of action of naltrexone is at the Toll-like receptor (TLR4) attached to the cell surface membrane of glia.

The ability to view activated glia would help greatly in treatment of so many conditions including neuropathic pain.


I was thinking about trying this drug myself but havent seen much on it for nerve pain. I spoke to a doctor who thinks my burning/allodynia is from neuroinflamation. There really isnt many drugs on the market that target this. I was told that in the next few years some may come out as they are in clinical trials.

bent98 10-12-2012 02:05 PM

http://en.wikipedia.org/wiki/Allodynia

I forgot to mention, my issue is with Allodynia and this wiki seems to explain that there are links at a cellular and molecular level.


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