NeuroTalk Support Groups - Once supplement regimine started, how long until results are seen? (vit B, etc)

NeuroTalk Support Groups (https://www.neurotalk.org/)

- Peripheral Neuropathy (https://www.neurotalk.org/peripheral-neuropathy/)

- - Once supplement regimine started, how long until results are seen? (vit B, etc) (https://www.neurotalk.org/peripheral-neuropathy/185423-supplement-regimine-started-results-seen-vit-etc.html)

Once supplement regimine started, how long until results are seen? (vit B, etc)

I started taking a nerve supplement formula about 10 days ago. It has a bunch of stuff in it, I can post the link later as my husband bought it. It has the methyl form of B12, alpha lipolic acid and a bunch of other things I know I should take that has been mentioned here. How long does it take for these things to become affective? My B12 was 350-ish, not horrible but still too low. The instructions we got from the company was to take a lot for two weeks, then a little less for two weeks, then maintain it at a couple pills a day, obviously to get these things in my body and then keep those levels up, I assume.

A couple weeks, a couple months, longer? I'm still trying to figure out if it's the myelin sheath that's messed up or if it's axonal (which then I would believe would make this hereditary for sure?) From what I've read, if it's axonal, all the vitamin B12 in the world won't help it. I can't stand pills, so if I don't have to take them, I won't. If it's a matter of taking them every day for a few months to find out, then I just need to know to persevere.

Actually B12 is involved in myelin repair. So axonal damage would be improved if the other factors are present. It is the axon that has the myelin.

Fishoil for the omega-3s, and B6, are the other things for myelin. Sometimes antioxidants like Vit C are suggested too.
http://www.ncbi.nlm.nih.gov/pubmed/15896807

Quote:

J Neurol Sci. 2005 Jun 15;233(1-2):93-7.
Vitamin B12, demyelination, remyelination and repair in multiple sclerosis.
Miller A, Korem M, Almog R, Galboiz Y.
Source

Division of Neuroimmunology and Multiple Sclerosis Center, Carmel Medical Center, Haifa 34362, Israel. millera@tx.technion.ac.il
Abstract

Multiple Sclerosis (MS) and vitamin B12 deficiency share common inflammatory and neurodegenerative pathophysiological characteristics. Due to similarities in the clinical presentations and MRI findings, the differential diagnosis between vitamin B12 deficiency and MS may be difficult. Additionally, low or decreased levels of vitamin B12 have been demonstrated in MS patients. Moreover, recent studies suggest that vitamin B12, in addition to its known role as a co-factor in myelin formation, has important immunomodulatory and neurotrophic effects. These observations raise the questions of possible causal relationship between the two disorders, and suggest further studies of the need to close monitoring of vitamin B12 levels as well as the potential requirement for supplementation of vitamin B12 alone or in combination with the immunotherapies for MS patients.

PMID:
15896807
[PubMed - indexed for MEDLINE]

I am skeptical about the mixture products. Often their websites lack accurate information. So hence I wonder if all the stuff is in there correctly. For example, they don't say to take on an empty stomach which is very important for the B12 to be even absorbed, as well as the alpha lipoic they include.

The only way to know if there is B12 in there is to have another test. Taking high dose B12 should put you over 1000 in 3 months or less.

There is no way to tell everyone what to do as you repeated here because everyone is different. Only testing will show for sure.

It does take time for things to improve. But many people who come here start to feel something improving in a month or so.

I got immediate relief when I started taking benfotiamine. I truly felt it was a miracle from the first day of taking them.

Potassium gives me fast relief for muscle spasms in my calf and arches.

Magnesium and even faster epsom salts bath gives good relief for a couple things.

I can't say if B12 does anything for me or not but I keep taking it.

I cant take rlipoic, gives me acid reflux.