NeuroTalk Support Groups

NeuroTalk Support Groups (https://www.neurotalk.org/)

- Tourette Syndrome (https://www.neurotalk.org/tourette-syndrome/)

- - adults? (https://www.neurotalk.org/tourette-syndrome/189441-adults.html)

can you recommend a site for adults dealing with tourettes? Also, I have both vocal tics and physical ones, but It didn't develop until I was an adult and took the antibiotic called avelox, now I think its been taken off the market. I don't know what else to call it but tourettes. I take tenex and also risperdone for the tics, When they started they were severe. No usually under control.

Hi Knitknut,
Welcome to the NeuroTalk Support Groups.

Sorry to hear of your experience with the medication that brought on your tics. That's pretty terrible but not unheard of that's for sure.

There are some other adults who drop by here from time to time. I'm hoping they will see your post and reply as well.

Quote:

Originally Posted by Lara (Post 989254)

Really? others have had that happen to them, starting after a medication? The doctors acted like that was just not possible at first. But here I am ticcing years and years after taking that one stinking pill

Hi Knitknut,
I perhaps wasn't clear in my post, I'm sorry.

Yes, it is possible to develop tics or tic-like symptoms after taking certain medications.

My sentence about the other adults who drop by here from time to time wasn't related to that in particular. I just meant that other adults who have tics post here from time to time.

There are Primary Tic Disorders and there are Secondary Tic Disorders.

Tardive Dyskinesia is another condition that occurs in some people who have reacted badly to certain medications. Dystonia is another condition. Both can appear a little similar to some types of sustained complex tics. Typically, TS appears in childhood and involves both phonic/vocal tics and motor tics that last for longer than a year and typically the tics wax and wane over time. Adult onset of TS isn't that common.

Tourettism is a term sometimes used for the appearance of tics secondary to some other cause.

http://www.scielo.br/pdf/rbp/v27n1/23707.pdf
Rev Bras Psiquiatr. 2005 Mar;27(1):11-7. Epub 2005 Apr 18.
Secondary tics and tourettism.
Mejia NI, Jankovic J.

Quote:

Amphetamines, cocaine, heroin, methylphenidate,
pemoline, levodopa, anti-depressants, carbamazepine,
phenytoin, phenobarbitol, lamotrigine, dextroamphetamine,
and other dopamine blocking agents (DRBD, neuroleptics)
have been reported to induce or exacerbate tics.

Quote:

Tardive tourettism due to exposure to dopamine receptor
blocking drugs (DRBD) or neuroleptics has been also reported

This is old now... from 1997 but lists certain medications shown at that time to have induced movement disorders
http://www.ncbi.nlm.nih.gov/pubmed/9098656
Drug Saf. 1997 Mar;16(3):180-204.
Drug-induced movement disorders.
Jiménez-Jiménez FJ, García-Ruiz PJ, Molina JA

Int Clin Psychopharmacol. 2005 May;20(3):177-8.
The emergence of tics during escitalopram and sertraline treatment.
Altindag A, Yanik M, Asoglu M.
http://www.ncbi.nlm.nih.gov/pubmed/15812270

Old too...
http://www.ncbi.nlm.nih.gov/pubmed/3731009
Can J Psychiatry. 1986 Jun;31(5):419-23.
Anticonvulsant medications: an iatrogenic cause of tic disorders.
Burd L, Kerbeshian J, Fisher W, Gascon G.

Just examples. There are at least 17,000 citations in PubMed for drug induced movement disorders.

http://www.nlm.nih.gov/medlineplus/d...s/a600002.html
Moxifloxacin (Avelox) Drug Info from MedlinePlus

So, Yes... It is possible to develop a movement disorder after taking certain medications. Have you seen a Neurologist? What sort of movements do you have exactly and what makes you think you have Tourette's Syndrome? So sorry about all the questions, :o but if I was you I'd be trying to sort out exactly what's gone on. Avelox is used for bacterial infections. I'm also curious if you had anything like Rheumatic Fever in your childhood or if you've ever had positive Strep tests.

http://www.ncbi.nlm.nih.gov/pubmed/23151468

Clin Neuropharmacol. 2012 Nov-Dec;35(6):292-4. doi: 10.1097/WNF.0b013e31826ba0eb.
Orofacial dyskinesia after moxifloxacin treatment--a case with normal hepatorenal function and review of literature.
Mittal SO, Machado DG, Jabbari B.
Source

Department of Neurology, Yale University School of Medicine, New Haven, CT

Quote:

RESULTS:

Discontinuation of moxifloxacin and treatment with clonidine resulted in significant reduction of orofacial dyskinesia over the period of 8 to 12 weeks. A review of literature shows reports of a variety of involuntary movements with third-generation fluoroquinolones, mostly manifesting in patients with impaired renal and kidney function.

I did a little digging but found this... it pertains generally to the class of drug called fluoroquinolones which includes Moxifloxacin (Avelox). I can't see specific mention of Moxifloxacin there but my eyes are playing tricks on me this morning. ;)

Excerpt from book
Drug Induced Movement Disorders
Therapeutics of Parkinson's Disease and Other Movement Disorders
edited by Mark Hallett, Werner Poewe

Knitknut. Welcome to a wonderful bunch of folks. Glad to have ya