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Supplements on empty stomach or not?

I have now received my:

R-Lipoic Acid 100mg
Benfotiamine 150mg
Jarrow B Right
Acetyl-L-Carnitine 250mg
Methyl B12 5000mcg

I would appreciate any help on what dosage to take and whether it should be on an empty stomach or with food as some of them say either but I want to get the best out of them that I can.

I had been diagnosed with PN from an EMG test but no idea what caused it and just have sunburn type pain on legs but loss of sensation on legs/feet/up to waist but no pain thank goodness.

I really hope the above will repair some of the damage and would appreciate hearing the best way to take them to maximise the results.

Thanks in advance.

I will put my suggestions in red in this quote:

Quote:

Originally Posted by superstar (Post 994351)

I have now received my:

R-Lipoic Acid 100mg (there are studies suggesting loss of absorption of this with food. So on an empty stomach might be best 100mg a day is usually enough)

Benfotiamine 150mg ( there are studies that say food or not, doesn't matter with this supplement 300mg a day to start, then can reduce to 150 later)

Jarrow B Right (most B vits go best with food-- the B12 in this is quite low anyway, so it does not matter much since you are taking B12 separately anyway--one a day)

Acetyl-L-Carnitine 250mg (may take with food, and food will offset any GI side effects that occur with some people--start at 250mg a day and work up by 250mg a day to 2 grams if needed --you may find lower doses work well, so increase weekly only or every other week)

Methyl B12 5000mcg (this has to be taken on an empty stomach for best absorption --food will block passive absorption in the intestine, but not if intrinsic factor is working properly--one a day and may reduce to 1000mcg after good levels are reached. You can do 5,000mcg twice a week then or 1000mcg daily)

I would appreciate any help on what dosage to take and whether it should be on an empty stomach or with food as some of them say either but I want to get the best out of them that I can.

I had been diagnosed with PN from an EMG test but no idea what caused it and just have sunburn type pain on legs but loss of sensation on legs/feet/up to waist but no pain thank goodness.

I really hope the above will repair some of the damage and would appreciate hearing the best way to take them to maximise the results.

Thanks in advance.

Thank you for the information Mrs. D. I took 300mg of Benfotiamine this morning (I had only been taking 150g) and within 5 minutes my face was burning and bright red, I can only assume it was that as yesterday I just took the smaller dose of all the supplements and was fine and that is the only thing I did differently. Hopefully it will go away soon and I think I will take them as two x 150mg rather than 300mg all in one go in the future.

You can take 150mg of benfotiamine and not increase it.
The websites about it suggest 600mg a day, and one person came on here once who used 1,200mg.
Because this form is not so quickly excreted, I never recommend more than 300mg and that is only to get you started.

No one here has ever had a side effect from it like that.

It is possible you don't need a high amount or any for that matter, and the thiamine in the B-right might be enough for you.

So one thing you can do is drop it entirely for now, and reintroduce it in a week. See if you get any flushing with 150mg.

The flushing side effect is most common with niacin. There is 25mg of Niacin and 25mg of non flush niacin in that B-right.
Most people will not flush at 25mg but it is possible.
http://www.jarrow.com/product/57/B-Right

If you think the flush is from the B-right, try it every other day instead of daily.

Thank you, I will maybe drop the B Right tomorrow and see if I still get the flush with 150mg of Benfotiamine. I took 150mg of it yesterday and the B Right with no problems which is why I thought maybe it was 300mg of Benfotiamine that did it today. It lasted about 45 minutes and was quite unpleasant.

That sounds like a niacin flush.... B-right has a good mixture of items and doses. Not very many people flush on 25mg of niacin but some do. I think it is about the best B complex on the market...not too strong and not too weak.

The niacin flush can be blocked with an aspirin taken 1/2 to 3/4 of a hour before the niacin.

But juggling your times or dropping one or the other may help.
Benfotiamine is not linking to flushing and I have read many papers on it. Also if the niacin is the culprit, most people do develop a tolerance to that side effect.