Adamas Initiates Phase 3 Trial of Parkinson's Drug
Adamas Pharmaceuticals Inc. announced that it has initiated a pivotal Phase 3 clinical study of ADS-5102 (amantadine HCl), a high-dose, controlled-release version of amantadine for the treatment of patients with Parkinson's disease who have developed levodopa-induced dyskinesia (LID).
http://www.dddmag.com/news/2014/06/a...4&location=top |
Question?
Amantadine helped control my dyskinesias somewhat, and mine can be so bad (and painful) that I would welcome anything! However, after my second week on Amantadine, my legs and feet swelled painfully and I had to stop the Amantadine.
Does anyone know if the "new and improved" Amantadine has similar side effects? Or does anyone know of something else that might be causing the swelling of my lower extremities? I take Sinemet, Comtan, Requip as my regular Parkinson's regime. Peggy |
Quote:
Gary |
Peripheral edema
Three volunteers 0f the total group (N = 83) suffered from peripheral edema as an adverse side effect. Unfortunately, I don't know how that compares percentagewise with the original drug formulation. However, although only a small percentage (3.6%), it appears that some people will have lower limb swelling as a side effect.
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Thanks
Thank you, Gary. I guess I will just have to give the drug a trial run and hope for better results.
Thank you, also, anagirl for the link. Peg |
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