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-   -   2 year safinamide study results (https://www.neurotalk.org/parkinson-s-disease/207506-2-safinamide-study-results.html)

lab rat 07-30-2014 02:26 PM

2 year safinamide study results
 
http://www.ncbi.nlm.nih.gov/pubmed/25044402

johnt 07-30-2014 02:54 PM

Some background:

"Safinamide is a reversible and selective monoamine oxidase B inhibitor, reducing degradation of dopamine, and a glutamate release inhibitor. ... It also seems to inhibit dopamine reuptake. ... Additionally, safinamide blocks sodium and calcium channels."
http://en.wikipedia.org/wiki/Safinamide

Many of us have taken rasagiline and selegiline which are also selective MAO-B inhibitors.
http://en.wikipedia.org/wiki/Monoami...dase_inhibitor

John


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