|
CLINICAL TRIAL...PD Associated Risk Study (PARS): Eval. Potential Screening Tools
1 Attachment(s)
Parkinson Associated Risk Study (PARS): Evaluating Potential Screening Tools for Parkinson's Disease
Official Study Title: Parkinson Associated Risk Study (PARS): Evaluating Potential Screening Tools for Parkinson's Disease Sponsor: Department of Defense Clinicaltrials.gov ID: NCT00387075 Study ID: 135 Trial Start Date: 15 Jan 2007 Last Updated Date: 13 Apr 2007 Trial Post date: 10 Apr 2007 Website URL: http://www.pdtrials.org/front/trial_...p?trial_id=135 Summary This study is designed to test the strategy of combining two biomarkers of parkinsonism, olfaction (sense of smell) and brain imaging in first-degree relatives of people with Parkinson’s disease (PD) as a tool to establish an ‘at risk’ PD cohort without motor symptoms of PD. The PARS Study is the largest long-term study in the United States of relatives of individuals with PD. It will evaluate a maximum of 7,500 relatives for 3-5 years, and follow a group of 300 individuals over a two year period, to determine whether specific tests are able to predict who may be at increased risk for developing PD. The goal of the PARS study is to better understand who is at risk for PD so that it can ultimately be prevented before it starts. The initial tool to be evaluated will be a test of the sense of smell. First-degree relatives of someone who has PD who are interested in this study will be asked to complete a form with their contact information. Eligible participants will be sent a scratch-and-sniff smell test and a brief questionnaire to be completed at home. Eligible participants may also be contacted to continue the mail-in questionnaires annually or to be evaluated by a neurologist near their home. Some individuals may be asked to undergo more extensive testing, including brain imaging using a radioactive labeled drug, [123I]b-CIT. The level of participation is optional. Enrollment Expected Enrollment: 300 Trial Phase Study Phase: Not Specified (About Phases) Symptoms # Trial does not treat PD symptoms Time Commitment Length of Time Commitment: More than six months Frequency of office visits:
Eligibility Trial accepts healthy volunteers Inclusion Criteria
Susan Mendick Director, Clinical Imaging Programs Management The Institute for Neurodegenerative Disorders Phone : 203-401-4300 smendick@indd.org 60 Temple Street, Suite 8B New Haven, CT 06510 USA Local Contacts Mayo Clinic Arizona 13400 E Shea Blvd. Scottsdale, AZ 85259 USA UCLA Medical Center Reed Neurological Research Center 710 Westwood Plaza A-253 Los Angeles, CA 90095 USA San Francisco VA PADRECC 4150 Clement Street 127P San Francisco, CA 94121 USA The Parkinson's Institute 1170 Morse Avenue Sunnyvale, CA 94089 USA USF Parkinson's Disease & Movement Disorders Center 4 Columbia Drive Suite 410 Tampa, FL 33606 USA Emory University Wesley Woods Health Center 1841 Clifton Rd. 3rd Fl Atlanta, GA 30329 USA Medical College of Georgia 1429 Harper Street HF 1121 Augusta, GA USA Northwestern University 710 No. Shore Lake Dr. Abbott Hall, 11th Fl. Chicago, IL 60611 USA Boston University Medical Center Dept of Neurology 715 Albany Street, C329 Boston, MA 02118 USA UNC Department of Neurology Movement Disorders Clinic 3114 Bioinformatics CB #7025 Chapel Hill, NC 27599 USA Beth Israel Medical Center 10 Union Square East Suite 5H New York, NY 10003 USA University of Rochester 919 Westfall Road Bldg C Suite 220 Rochester, NY 14618 USA Portland VA Medical Center PADRECC 3710 SW US Veterans Hospital Road P3-PADRECC Portland, OR 97239 USA Parkinson's Disease and Movement Disorders Center 330 S. 9th Street Philadelphia, PA 19107 USA Neurohealth 227 Centerville Road Warwick, RI 02886 USA Michael E. DeBakey VA Medical Center 2002 Holcombe Blvd. PADRECC Neurology Care Line 127PD Houston, TX 77030 USA Hunter Holmes McGuire VA Medical Center 1201 Broad Rock Blvd. Richmond, VA 23249 USA Attachment 1411 Full Details: PDTrials.org http://www.pdtrials.org/front/trial_...p?trial_id=161ClinicalTrials.gov http://clinicaltrials.gov/ct/show/NCT00427674?order=1[LIST][*]Complete list of PD trials Attachment 1411 Parkinson Pipeline Project www.pdpipeline.org Following theapies from pre-clinical development to approval in the Parkinson Pipeline Project Database (see homepage for link to database) Attachment 1411 |
| All times are GMT -5. The time now is 06:49 PM. |
Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
vBulletin Optimisation provided by
vB Optimise v2.7.1 (Lite) -
vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.