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-   -   Duloxetine ???? (https://www.neurotalk.org/medications-and-treatments/209505-duloxetine.html)

Johnsonsyard 09-15-2014 01:00 PM

Duloxetine ????
 
Hi Everyone, Have taken along time to get off Lyrica after severe reactions. Doc now suggesting Duloxetine. Whats this all about ? Is it safe ? My Neuropathic pain has returned with muscle spasms around face and neck.


Regards


Nick

Dr. Smith 09-15-2014 05:55 PM

Duloxetine (Cymbalta) is an SNRI antidepressant. Like Lyrica, it has helped—and is helping—a great many people, however also like Lyrica, some people are finding it very difficult to get off of (among other issues). I'm not suggesting this would/will happen to you, but I think considering your experience, it's something you should be aware of.

Here is one report about Duloxetine Discontinuation Syndrome isued by the American FDA.

duloxetine

snri

serotonin syndrome

duloxetine discontinuation syndrome

Doc

anon1028 09-15-2014 05:58 PM

Quote:

Originally Posted by Dr. Smith (Post 1096715)
Duloxetine (Cymbalta) is an SSRI antidepressant. Like Lyrica, it has helped—and is helping—a great many people, however also like Lyrica, some people are finding it very difficult to get off of (among other issues). I'm not suggesting this would/will happen to you, but I think considering your experience, it's something you should be aware of.

Here is one report about Duloxetine Discontinuation Syndrome isued by the American FDA.

duloxetine

ssri

serotonin syndrome

duloxetine discontinuation syndrome

Doc

snri. they just took me off it and put me on Zoloft but it was very effective for a number of years

Dr. Smith 09-16-2014 12:53 AM

Quote:

Originally Posted by markneil1212 (Post 1096717)
snri.

That's correct; Thank you. (I corrected my previous reply)
Aside from that, everything else still holds.

Quote:

they just took me off it and put me on Zoloft but it was very effective for a number of years
??? :Hum: ...Just took you off what, the Lyrica or duloxetine? Zoloft/sertraline IS an SSRI; same admonishments/concerns as above.

Are they putting you on sertraline or duloxetine for depression, pain, Lyrica withdrawal or what?

Doc

Johnsonsyard 09-17-2014 02:32 PM

Dr Smith duloxetine
 
Quote:

Originally Posted by Dr. Smith (Post 1096715)
Duloxetine (Cymbalta) is an SNRI antidepressant. Like Lyrica, it has helped—and is helping—a great many people, however also like Lyrica, some people are finding it very difficult to get off of (among other issues). I'm not suggesting this would/will happen to you, but I think considering your experience, it's something you should be aware of.

Here is one report about Duloxetine Discontinuation Syndrome isued by the American FDA.

duloxetine

snri

serotonin syndrome

duloxetine discontinuation syndrome

Doc


Hi Doc , Thanks. You express my concerns exactly. Been to Homeopath . Have you used them ? A number of suggestions being made including pregabalin in homeopathic potency . Have you heard of this. I feel as though my system is very hypersensitive after what I've been though so far and aI am very cautious. Own Doc basically taking attitude now of leaving all decisions to me after the carry on with the Lyrica. They seem a bit scared after me last reactions.

Thanks

Nick

Johnsonsyard 09-17-2014 02:34 PM

Duloxetine markneil
 
Quote:

Originally Posted by markneil1212 (Post 1096717)
snri. they just took me off it and put me on Zoloft but it was very effective for a number of years

HI there, did not know that this was an SSRI. Once took this years ago and was VERY ill.

Just seen other post saying SNRI . Isthis like an SSRI ?

THanks


Nick

Lara 09-17-2014 02:50 PM

Difference between SNRI and SSRI

The SSRIs affect serotonin selectively and the SNRIs work a little differently and no so selective.

from Mayo Clinic - scroll down each webpage to section to

How SNRIs work

How SSRIs work

Dr. Smith 09-18-2014 09:31 AM

Quote:

Originally Posted by Johnsonsyard (Post 1097178)
Hi Doc , Thanks. You express my concerns exactly. Been to Homeopath . Have you used them ? A number of suggestions being made including pregabalin in homeopathic potency . Have you heard of this. I feel as though my system is very hypersensitive after what I've been though so far and aI am very cautious. Own Doc basically taking attitude now of leaving all decisions to me after the carry on with the Lyrica. They seem a bit scared after me last reactions.

Thanks

Nick

Nick,
I don't buy into the whole concept; IMO, homeopathy is quackery. http://images.paraorkut.com/img/emot...g_duck-117.gif

OTOH, if the doctors who say that, 'Lyrica withdrawal/discontinuation syndrome is all in a patient's mind' are correct, then homeopathy—which is also all in the patient's mind—may be a valid treatment/cure. :rolleyes: If so, it could validate those doctors' claims/positions for those patients.

Doc

Lara 09-18-2014 02:49 PM

:confused:

I know people who use homeopathy for various different ailments and they find it helpful.

Jomar 09-18-2014 11:24 PM

Quackwatch...:(
I read on his site long ago, but made my own decisions after actually studying & trying various therapies etc. that he pooh poohed... and they worked and helped for me.

I will say that much depends on the practitioner, communication, and follow thru.


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