More detail on reversing Alz., the program
 

Here is another article discussing in more detail the article about reversing Alz. that was posted today:

http://www.impactaging.com/papers/v6...ll/100690.html

The program is set out in a chart format in the article, with the rationale for each part.

I am so happy some doctors are looking at the whole body instead of one part at a time:)

Interesting, thanks!

Here's the spin I'd put on it from the PD point of view.

Crucial to the pathogenesis of PD is the death of dopaminergic neurons, most importantly in the substantia nigra, but also in the rest of the brain and in the enteric nervous system. Even in one person there is no single cause: genetics, environment and diet all play a part. The effects of ageing are essential. Even added together all these processes would be insufficient to cause PD, except, perhaps, in extreme old age. To get the disease there needs to be a positive feedback mechanism. (Note "positive" here does not mean a good outcome but, rather, that the disease feeds on itself.) In PD this is performed by the misfolding of alpha-synuclein. Thus, rather than think of the cause or even the causes of PD, it is better to think of the disease as a process.

The import of the AD results is that a multi-pronged attack on all points in the process can slow the progression of the disease, even in those people who have symptoms bad enough to be diagnosed, to an extent where the brain's plasticity is sufficient for symptoms to be reversed.

If this hypothesis applies to PD, we need to identify, perhaps, 20 small wins. Things like exercise. The problem is that the clinical trial process is neither responsive nor sensitive enough to do this in a short period of time.

If we, PwP, are to get this soon, we need to work together now.

John

The 2014 article you posted on AD was extremely interesting, lurkingforacure. There's a new one out now by the same researchers:

Reversal of cognitive decline in Alzheimer?s disease - AGING Journal (June 2016)

Since AD and PD are both neurodegenerative diseases and both can lead to significant cognitive decline, I am open to the possibility that what helps people with AD might also help people with PD.

In support of this possibility, the man in the UK who reversed his PD symptoms ...
http://www.neurotalk.org/parkinson-s...arkinsons.html
... used a comprehensive supplement protocol which had many of the same elements as Dr. Bredesen's M.E.N.D. protocol against AD.

Does anyone else find this interesting?

Thanks for this, Bergamotte. When I printed out the 2014 version PDF, there were some strange, extraneous marks on parts of the manuscript that made it difficult to read the abstract and references. The newer version did not show any such marks.

Maybe it's just my printer!

Robert