Genetic and methylation profile
 

Just received preliminary results of my genetic screening. My methylation profile shows some mutations, actually a lot of them. Two homozygous, which are supposed to be more serious, and a lot of heterozygous. Can anyone help with analysing them? The information I received is a bit overwhelming, since it is all new to me. A quick, superficial read suggests I may have issues with vitamines D3, B12 and methylfolate.

One really good podcast is by a group of functional medicine doctors at The Center for Bio-individualized Medicine. You can find it on iTunes or can steam it from their website. They have lots of information on reading and interpreting your 23andme genetic profile; they have talked extensively about methylation. You could also goggle methylation on iTunes and see if other podcasts. Good luck.

So you will have to add methylfolate to your supplements
And raise your B12 to 5 mg a day at least.

Exactly, methylfolate was what I am thinking of.

Thanks; can you please send me the url of their website, with that podcast?

Interestingly enough, it also shows a mutation which makes me vulnerable to celiac disease/ gluten sensitivity, and also some vitamine D absorption issues. I'll get them both tested.

Good thing you got the testing... now you can work around the mutations perhaps and regain some lost functions.

If you have Celiac and don't know it, you could be malabsorbing many other nutrients. So going gluten free may be a good idea, too.

Been doing that already, but not very religiously. Now I have a reason to be systematic about it.

That spells no more eating out so much :( Which is not a good news, because cooking with two bad hands is a pain in the .. hands. Can anyone recommend a good cooking book for going gluten-free?

There are a lot of sites on line for gluten free, and many restaurants are now offering a gluten free menu to accommodate their patrons. Both Sam's and Costco offer a variety of GF these days. It's a lot easier to be GF today than just a short time ago.