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- Thoracic Outlet Syndrome (https://www.neurotalk.org/thoracic-outlet-syndrome/)

- - Urls's needed (https://www.neurotalk.org/thoracic-outlet-syndrome/21899-urlss.html)

Does anyone have specific links to TOS in relating to the nervous and ciculatory system?
Here's what i'm looking for:
TOS nerve and blood vessel compressions cause numbness in toes, sciatic, stomach aliments, headaches, ear swishing, eye blurriness, neck and trap pain and blood clots.

as u know it "pains" me to be on the compooper much and if someone else has a direct link that would be much easier on my body.

Upper Extremity Sx

www.tos-syndrome.com/newpage12.htm

NOW I NEED LOWER EXTREMITY SX PAGE

I don't recall reading about lower body sx on any of the sites- so far the only place I have heard about it spreading is the anecdotal stories here on the forum.
I did a very quick search on PubMed = TOS lower body sx ? but nothing related came up.

Maybe a search on articles by Roos, Sanders - I don't know if Brantigan or Annest have articles out on the subject. Does Ellis find that the spread can happen?

another option - email each of them and ask if they can point you to any studies or documentation relating to that.

Cannot Find Any Medical Literature On Lower Body Sx

http://tosinfo.com/mri/images/jnma_tos_article_0403.pdf you might want to copy/paste this into the address if it won't come up for you let me know

and I got this from Our Dear OCGirl :)

The Role of Bicuspid Valves in Costoclavicular
Venous Compression in Patients with thoracic
Outlet Syndrome (TOS)
Poster submission
Ernestina H. Saxton; James D. Collins; Theodore Q. Miller;
Samuel S. Ahn; A. Carnes. Los Angeles, CA
The circulatory system is a closed system.
Compression of any peripheral vein decreases
venous return, and increases intrathoracic, intraabdominal,
and intracranial pressures. Veins contain
bicuspid valves along their course to assist and direct
blood flow, and divert pressure into other veins and
the lymphatics. Every vein has a bicuspid valve proximal
to its junction with another vein. Compression
of the bicuspid valves diminishes and/or obstructs
venous and lymphatic return to the heart; veins and
lymphatics dilate and tissues from whence they came
expand (edema). Ischemia develops, and, if not
relieved, tissue damage follows. Veins are compressed
in patients with TOS. This results in patients’
complaints of numbness, tingling, pain of the upper
and lower extremities, headache, back and face pain,
visual symptoms, incoordination, syncope, and
weakness. Monitored multiplanar bilateral MRI,
MRA and MRV display sites of bicuspid valve compression
in patients with brachial plexopathy and
TOS. Patients were imaged on the 1.5 Tesla GE Signa
MRI unit, 4.0-mm thickness, with saline water bags
beside the neck to enhance signal-to-noise ratio. This
presentation displays the sites of bicuspid valves
within the internal and external jugular; subclavian
and cephalic veins in the neutral position and sites of
compression in stressed position. It also displays role
of the vertebral veins in collateral circulation with
costoclavicular compression.
Transient Ischemic Attack (TIA) Symptoms
Caused by Costoclavicular Venous
Compression in Patients with Thoracic Outlet
Syndrome (TOS): MRI/MRA
Poster submission
James D. Collins; Ernestina H. Saxton; Theodore Q. Miller;
Samuel S. Ahn; A. Carnes. Los Angeles, CA
Transient ischemic attack (TIA), usually thought
of as a sudden focal loss of neurological function with
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION VOL. 95, NO. 8, AUGUST 2003 683
ABSTRACTS
complete recovery usually with 24 hours, is caused by
a brief period of inadequate perfusion of the brain in
the territories of carotid and vertebral basilar arteries.
Patients with thoracic outlet syndrome (TOS) present
with TIA-like symptoms: visual scotomata, double
and blurred vision, vertigo-dizziness, tinnitus, slurred
speech, incoordination/abnormal gait, numbness,
syncope, and headache. Electromyography/nerve
conduction studies, (EMG/NCV), routine x-rays, CT,
MRI/ MRA, and cerebral angiography are negative.
Monitored bilateral multiplanar MRI, MRA and
MRV on the 1.5 Tesla GE MRI unit display costoclavicular
compression of the bicuspid valves within
the draining veins of the neck, shoulders, and the
upper extremities that trigger the same complaints
that occur in patients with TIA, particularly in the
abduction external rotation (AER) of the upper
extremities. This presentation displays enhanced costoclavicular
compression with AER of the bicuspid
valves within the internal jugular and subclavian
veins and collateral venous return through vertebral,
cephalic, and anterior jugular veins—triggering TIA
complaints. Since the circulatory system is a close
system, compression of the neck veins significantly
impairs cerebral venous drainage and triggers TIA
compliants.

I know that there are experiments with rats given RSI's that show the rats develop lower body symptoms. I believe but am not sure that this is related to the body wide inflammatory response cause by RSI.

Details are probably in one of these papers.

1: J Orthop Res. 2003 Jan;21(1):167-76.
Chronic repetitive reaching and grasping results in decreased motor performance and widespread tissue responses in a rat model of MSD.
Barbe MF, Barr AE, Gorzelany I, Amin M, Gaughan JP, Safadi FF.
Department of Physical Therapy, College of Allied Health Professions, Temple University, 3307 North Broad Street, Philadelphia, PA 19140, USA. mbarbe@temple.edu
This study investigated changes in motor skills and tissues of the upper extremity (UE) with regard to injury and inflammatory reactions resulting from performance of a voluntary forelimb repetitive reaching and grasping task in rats. Rats reached for food at a rate of 4 reaches/min, 2 h/day, and 3 days/week for up to 8 weeks during which reach rate, task duration and movement strategies were observed. UE tissues were collected bilaterally at weekly time points of 3-8 weeks and examined for morphological changes. Serum was tested for levels of interleukin-1alpha (IL-1) protein. The macrophage-specific antibody, ED1, was used to identify infiltrating macrophages and the ED2 antibody was used to identify resident macrophages. Rats were unable to maintain baseline reach rate in weeks 5 and 6 of task performance. Alternative patterns of movement emerged. Fraying of tendon fibrils was observed after 6 weeks in the mid-forelimb. After 4 weeks, a general elevation of ED1-IR macrophages were seen in all tissues examined bilaterally including the contralateral, uninvolved forelimb and hindlimbs. Significantly more resident macrophages were seen at 6 and 8 weeks in the reach limb. At 8 weeks, serum levels of IL-1alpha increased significantly above week 0. Our results demonstrate that performance of repetitive tasks elicits motor decrements, signs of injury and a cellular and tissue responses associated with inflammation.
PMID: 12507595 [PubMed - indexed for MEDLINE]

Clin Sci (Lond). 2007 Mar;112(5):305-14.

Inflammatory biomarkers increase with severity of upper-extremity overuse disorders.

Carp SJ, Barbe MF, Winter KA, Amin M, Barr AE.

Department of Physical Medicine, Chestnut Hill Health System, 8835 Germantown Avenue, Philadelphia, PA 19118, U.S.A.

MSDs (musculoskeletal disorders) from overuse are common occupational health problems that cause pain, functional loss and loss of work time. The aim of the present study was to determine whether a relationship exists between the severity of early-onset overuse-related MSDs of the upper extremity and serum levels of IL-1beta (interleukin-1beta), TNF-alpha (tumour necrosis factor-alpha), IL-6 (interleukin-6) and CRP (C-reactive protein). Twenty-two subjects with upper-extremity MSDs due to overuse for no longer that 12 weeks were stratified according to the severity of upper-extremity signs and symptoms as determined by a UBMA (upper-body musculoskeletal assessment). Nine asymptomatic subjects also participated. Serum cytokines were analysed using ELISA, and CRP was analysed using a laser nephelometry technique. CRP was strongly correlated, and TNF-alpha, IL-1beta and IL-6 were moderately correlated, with UBMA scores. Only CRP and TNFalpha were significantly associated with UBMA scores in an ordinal logistic regression analysis in which age and BMI (body mass index) were covariates. These results are of clinical importance as they suggest that early-onset overuse-related MSDs may have an inflammatory component. The possibility of using a combination of serum biomarkers to follow the progression of overuse-related MSDs or their response to therapeutic intervention may be of interest to clinical practitioners and should be the focus of future research.

Publication Types:
· Research Support, Non-U.S. Gov't

MeSH Terms:
· Adult
· Biological Markers/blood
· C-Reactive Protein/metabolism
· Cumulative Trauma Disorders/blood*
· Female
· Humans
· Inflammation Mediators/blood*
· Interleukin-1beta/blood
· Interleukin-6/blood
· Male
· Middle Aged
· Occupational Diseases/blood*
· Severity of Illness Index
· Tumor Necrosis Factor-alpha/blood
· Upper Extremity*

Substances:
· Biological Markers
· Inflammation Mediators
· Interleukin-1beta
· Interleukin-6
· Tumor Necrosis Factor-alpha
· C-Reactive Protein

PMID: 17064252 [PubMed - indexed for MEDLINE]

: J Neuroimmunol. 2005 Oct;167(1-2):13-22
Increase in inflammatory cytokines in median nerves in a rat model of repetitive motion injury.
Al-Shatti T, Barr AE, Safadi FF, Amin M, Barbe MF.
Kuwait University, Faculty of Allied Health Sciences, P.O. Box 31470, Sulaibekhat, Kuwait 90805, Kuwait. mary.barbe@temple.edu
We examined cytokines in rat median nerves following performance of a high repetition reaching and grasping task at a rate of 8 reaches/min for up to 8 weeks. IL-1alpha, IL-1beta, TNF-alpha, IL-6 and IL-10 were analyzed by immunohistochemistry. Double-labeling immunohistochemistry for ED1, a marker of phagocytic macrophages, was also performed. We found increased immunoexpression of IL-6 by week 3, increases in all 5 cytokines by week 5. This response was transient as all cytokines returned to control levels by 8 weeks of performance of a high repetition negligible force task. Cytokine sources included Schwann cells, fibroblasts and phagocytic macrophages (ED1-immunopositive). These findings suggest that cytokines are involved in the pathophysiology of repetitive motion injuries in peripheral nerves.
PMID: 16026858 [PubMed - indexed for MEDLINE]

Try searching for posture alliegnment. If the neck is a turtle, and humped w from reverse curve...
Also Dr T says the trapizius is the coat hanger for the scapulas, and that it goes all the way to the waist, so if it is in spasms then the hipp, back, and legs...

Don;t foget at our age..over 20 we get some degeneration and from chronic pain and hunch over pain walking it can be secondary induced not the primary of TOS.

I think too, some meds can make the feet burn, tender, and problems with signals of pain....
See what I find.
Di

for headaches

: Headache. 1985 Jun;25(4):208-10.Links
Headache as the leading symptom of the thoracic outlet syndrome.
Raskin NH, Howard MW, Ehrenfeld WK.

PMID: 4019182 [PubMed - indexed for MEDLINE]

some of your other symptoms might be in

1: Vasc Endovascular Surg. 2006 May-Jun;40(3):251-4.
Thoracic outlet syndrome as a disorder of neurogenic inflammation.
Ellis W.

I am not sure, it's been awhile since I read it.

If you have trouble understanding articles, feel free to contact me, I usually have the background to read them.

good job ma-ladies
ur awesome