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-   -   Uric acid relates to dopamine transporter availability in Parkinson's disease (https://www.neurotalk.org/parkinson-s-disease/220521-uric-acid-relates-dopamine-transporter-availability-parkinsons-disease.html)

badboy99 05-20-2015 02:32 PM

Uric acid relates to dopamine transporter availability in Parkinson's disease
 
http://www.ncbi.nlm.nih.gov/pubmed/25288358

zanpar321 05-20-2015 03:06 PM

Quote:

Originally Posted by badboy99 (Post 1143411)

Lower levels of uric acid appear to associated with PD in these studies.

http://bmjopen.bmj.com/content/3/11/e003620.short

http://jpet.aspetjournals.org/content/324/1/1.full

A smaller study published last year also suggested that high uric acid levels could slow the progression of Parkinson’s Disease.

http://www.telegraph.co.uk/news/heal...sufferers.html

lurkingforacure 05-20-2015 03:07 PM

higher uric acid + different gut bacteria =?
 
Quote:

Originally Posted by badboy99 (Post 1143411)

This is interesting, and raises the thought that perhaps we should be looking at connections between the things we do know. For example, we know PWP have higher levels of uric acid in their blood AND a (recently discovered) substantially different mix of gut bacteria than nonPWP. How could these conditions be related? What might the combination of these two factors mean? Has anyone studied the gut biome of PWP whose uric acid measured in the high range, and if so, what were the findings? I think we could learn a lot more meaningful things about PD if we started looking at the relationships between the things we do know, now.

zanpar321 05-20-2015 04:07 PM

Quote:

Originally Posted by lurkingforacure (Post 1143413)
This is interesting, and raises the thought that perhaps we should be looking at connections between the things we do know. For example, we know PWP have higher levels of uric acid in their blood AND a (recently discovered) substantially different mix of gut bacteria than nonPWP. How could these conditions be related? What might the combination of these two factors mean? Has anyone studied the gut biome of PWP whose uric acid measured in the high range, and if so, what were the findings? I think we could learn a lot more meaningful things about PD if we started looking at the relationships between the things we do know, now.

Exactly Lurking! I have begun a compilation of things we know about PD earlier this year, things we think we know and additional things we would like to know. I hope to compile this in the next few months.

badboy99 05-20-2015 07:10 PM

Quote:

Originally Posted by lurkingforacure (Post 1143413)
This is interesting, and raises the thought that perhaps we should be looking at connections between the things we do know. For example, we know PWP have higher levels of uric acid in their blood AND a (recently discovered) substantially different mix of gut bacteria than nonPWP. How could these conditions be related? What might the combination of these two factors mean? Has anyone studied the gut biome of PWP whose uric acid measured in the high range, and if so, what were the findings? I think we could learn a lot more meaningful things about PD if we started looking at the relationships between the things we do know, now.

I believe PWP have lower levels of UA generally.

badboy99 05-20-2015 07:13 PM

Inosine raises your UA.


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