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-   -   Can Inosine Repair Nerve Damage? (https://www.neurotalk.org/general-health-conditions-and-rare-disorders/221595-inosine-repair-nerve-damage.html)

caroline2 06-14-2015 01:59 PM

Can Inosine Repair Nerve Damage?
 
This from Byron Richards site. I'm in my first month with Inosine and Sphingolin for the nerve damage I deal with from hip replacement. I may be noticing less burning and tingling:


http://www.wellnessresources.com/hea...r_nerve_damage...
Oct 27, 2009 - The research shows that Mst3B is stimulated by inosine, opening the door for a simple nutritional strategy to help regenerate nerve health.


Well, one can't get to this site this way, maybe someone else has the secret, but one can just google: Inosine and Nerve Damage and even add Byron Richards.

Lara 06-14-2015 03:01 PM

I think this is the link you've mentioned.

http://www.wellnessresources.com/hea..._nerve_damage/
Can Inosine Repair Nerve Damage?

caroline2 06-14-2015 03:03 PM

Yes, Lara, thank you thank you.

kiwi33 06-14-2015 06:08 PM

The two cited papers in the link are both in excellent journals.

There are a few others which suggest that inosine can help in animal models of repair of nerve injury - I can't find any about humans.

I don't know how common inosine deficiency is in humans - people who are deficient in it might benefit from taking it as a supplement but supplements would probably not help people with adequate inosine levels.

caroline2 06-14-2015 07:57 PM

I don't know how one knows if there is an inosine deficiency going on.

Just talking to a friend who has been dealing with diabetes as long as I've known her and she takes Metformin and says she has no nerve damage. I thought nerve damage and diabetes were a given.

kiwi33 06-17-2015 11:33 PM

Metformin is indicated for management of Type 2 (not Type 1) diabetes. It works by blocking glucose production (a process called gluconeogenesis) by the liver.

While Type 2 diabetes is a risk factor for neuropathy, my understanding is that this is not a "given".

You and your friend might find the information in this (long) link about Type 2 diabetes helpful; http://www.mayoclinic.org/diseases-c...n/con-20031902 .

caroline2 06-19-2015 12:56 PM

Just about finishing up 1st month on Sphingolin and Inosine and I "Think" I'm feeling less and less tingling and burning on my thigh. Going for month 2.

caroline2 07-21-2015 12:33 PM

Update: I just finished two months on Sphingolin and will not buy again now. Will continue with Inosine for at least another month and see how it goes...the tingle/burn is pretty much gone. Will it return? Don't know...time will tell. I will continue to do my research on these two nerve supps.

caroline2 08-21-2020 01:53 PM

Inosine and Inoitol are of the B8 family and YES many are deficient in the B vitamins...

kiwi33 08-21-2020 08:54 PM

There is some information about inosine here Inosine - an overview | ScienceDirect Topics and similarly for inositol here Inositol - Wikipedia.


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