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-   -   june mdscongress2015 LateBreakingAbstracts (https://www.neurotalk.org/parkinson-s-disease/221913-june-mdscongress2015-latebreakingabstracts.html)

soccertese 06-21-2015 10:53 AM
june mdscongress2015 LateBreakingAbstracts
 
http://www.mdscongress2015.org/Congr...actsPubDoc.pdf

abstracts from june congress, you might find something interesting, maybe not.

zanpar321 06-21-2015 11:33 AM
The Prothena alpha synuclein study results were quite interesting. Do lower levels of alpha synuclein equate to less or reversed PD symptoms? The real test for that will be in the next study when they use PD patients. Exciting!

Quote:
Originally Posted by soccertese (Post 1149686)
http://www.mdscongress2015.org/Congr...actsPubDoc.pdf

abstracts from june congress, you might find something interesting, maybe not.

Lana 06-23-2015 12:15 AM
Prothena poster
 
Quote:
Originally Posted by zanpar321 (Post 1149693)
The Prothena alpha synuclein study results were quite interesting. Do lower levels of alpha synuclein equate to less or reversed PD symptoms? The real test for that will be in the next study when they use PD patients. Exciting!
I have a pdf of the Prothena poster for the phase 1a. Tried to attach, and got a message that it exceeds the forum's limit. If anyone is interested I can email it.

zanpar321 06-23-2015 08:55 AM
Quote:
Originally Posted by Lana (Post 1150117)
I have a pdf of the Prothena poster for the phase 1a. Tried to attach, and got a message that it exceeds the forum's limit. If anyone is interested I can email it.
This recent study also seems to indicate that reducing alpha synuclein helps PD symptoms. At least in animals. Sure hope it's true in humans!

http://www.upmc.com/media/NewsReleas...e-therapy.aspx

zanpar321 06-23-2015 09:15 AM
Quote:
Originally Posted by Lana (Post 1150117)
I have a pdf of the Prothena poster for the phase 1a. Tried to attach, and got a message that it exceeds the forum's limit. If anyone is interested I can email it.
The Prothena study seems to show that alpha synuclein levels appear to slowly increase again after the PRX002 drug (which immediately drops alpha synuclein 96%) is introduced so a regime of once a month IV may be used to keep the alpha synuclein levels low. Could it be that keeping alpha synuclein levels down will prevent/reverse PD? Sure hope so!


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