Timespan Mestinon dosage
 

Hi all,
I have been adding more dosage of Mestinon for some time now. Started at 3 x 60 per day. Now up to 6 x 60.
I went to the Nuro last week, and they suggested I try the 180 Timespan, and drop 1 of the evening 60 mg. I have and seems to be better.
Have any of you used this Timespan, and if so how were you results.
Thanks FREDH

Yes, Timespan works good for me. I've been on several different meds over the past few years, including Imuran and Prednisone and have been able to get off those after increasing the Mestinon. I take 6 x 60 at intervals during the day and one 180 Timespan in the morning and one in the evening and so far so good! My tummy seems to tolerate the Timespan better than more of the 60's.
Good luck!

....Meant to write that I take 3 x 60 Mestinon (not 6 x 60) plus 2 x 180 Timespan a day and it covering my MG quite well, at least for now.

kjhawk5
 

Wow--when I saw that 6 x 60, I didn't know what to think. Anyway 3 x 60 sounds more like it. Thanks so much for this. I also didn't know you could take 2 Timespan a day. I have been worried that I was at max dosage. I have only ben on Timespan for 4 days, but feel better already. Thanks again.
Later -FREDH

Well 6 x 60 = 360 mg total, even with 2 x 180 timespan that would make 720 mg total.

3 x 60 + 2 x 180 is 540 mg.

I am on 6 x 90 mg = 540 mg, and that is not enough, probably going to have to increase to 6 x 120 = 720 mg total.

In actual fact the total per day is not really so important, because of the short half life of this medicine. What is more important is to have the needed level at regular intervals. Every 4 hours is the most common, but that can be as often as every 3 hours, or as long as every 6 hours.

Oh, and Timespan is designed to give you the same effect that 60 mg every 4 hours would give you. The idea being that you take it late at night and it covers you until you wake the next morning, so from 12 until 9.

julijayne,
I got the idea somewhere, that the most dosage taken per day should only be around 360 to 400. Thanks for this. Like you say it wears off in 11/2 or 2 hours anyway.
Thanks --FREDH

Translated from Dutch manufacturers information sheet;
Recommended dose is 30-60mg 3-4 times per day (480mg)
If needed increased to 5 - 20 (yes 20) x 60 mg per day!

20 x 60 = 1200mg per day.

Same perspective as Julie on Mestinon dosage. I'm at 540/day and my neuro said I could go up more if needed. My neuro is ok fine with the 2 Timespan/day - I take one in the morning and one in the evening. My digestive system seems to tolerate better than taking more of the 60 mg tabs. Take care

I tried it but I didn't really like it.
Now I'm on 5 - 7 x 70 normal mestinon. Dosage depends on how I feel and sometimes I take around 8 pm, 10.30 pm (in bed) and other days I take 6, 8, 10 pm so it's mostly the evenings that make the difference in how many times I take it

The timespan made me feel weird and jittery muscles.