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-   -   Fecal transplant (https://www.neurotalk.org/peripheral-neuropathy/228095-fecal-transplant.html)

baba222 10-30-2015 07:51 PM

Fecal transplant
 
Ok, maybe it is out there, any thoughts for sfn treatment?
TIA

Ragtop262 10-31-2015 12:10 AM

OK, I have to admit, I had to look this one up to make sure it was real. :confused:

What I found indicated it may have some value in Parkinsons disease, and possibly MS (CNS type issues) - but didn't see anything related to PN. Did you see some information that indicated it was useful in treating PN??

kiwi33 10-31-2015 02:14 AM

Faecal transplants work well for Clostridium difficile infection (about 85-90% effective).

They have been trialled for some neurological issues, including multiple sclerosis and Parkinson's disease but so far the evidence is inconclusive.

As far as I know they have not been tried for peripheral neuropathy. There is nothing in PubMed which suggests a link between the kinds of bacteria which normally live in the gut (the "gut microbiome") and peripheral neuropathy.

baba222 11-03-2015 05:49 PM

Quote:

Originally Posted by Ragtop262 (Post 1180731)
OK, I have to admit, I had to look this one up to make sure it was real. :confused:

What I found indicated it may have some value in Parkinsons disease, and possibly MS (CNS type issues) - but didn't see anything related to PN. Did you see some information that indicated it was useful in treating PN??

No, it seems like a lot of folks with SFN seem to have GI troubles or challenges prior.

Just throwing darts.

Neuroproblem 11-04-2015 05:11 AM

Quote:

Originally Posted by kiwi33 (Post 1180740)
Faecal transplants work well for Clostridium difficile infection (about 85-90% effective).

They have been trialled for some neurological issues, including multiple sclerosis and Parkinson's disease but so far the evidence is inconclusive.

As far as I know they have not been tried for peripheral neuropathy. There is nothing in PubMed which suggests a link between the kinds of bacteria which normally live in the gut (the "gut microbiome") and peripheral neuropathy.

Fecal transpplants was designed to restore the so-called flora of the gut nuked by antibiotics.. it wouldnt make sense that it would be related to autoimmune or neurodegeneration. Since these 2 diseases are from different origins. since MS is based recognizing parts of the spinal cord and brain as a "foreign invader", and parkinson is based of misfolded proteins in the brain. I see the benefits in using this to combat gi diseases, caused by bacteria or viruses, parasites though. There is also a risk of using someone elses fecal transplants, as they can carry pathogen in the excrements.

mrsD 11-04-2015 08:25 AM

New research is beginning to show that the gut microbes may be connected to autoimmune disease.

http://chriskresser.com/does-the-gut...mmune-disease/

and:
http://www.drperlmutter.com/new-clue...ns/?hvid=vRCqd

Whether this continues to show links to human autoimmunity, only time will tell.

But changing diet by avoiding sugar and excess carbs, already does change the gut flora, and improve many things.
If you do a good Candida cleanse you will notice some improvements in PN pain...like I do.
(NOW Candida Support)

DavidHC 12-14-2015 02:11 PM

I've done a great deal of research on this topic over the years and have been following the research. MrsD is right, and there's more and more research being published. The sooner conventional medicine realizes what traditional medicine has known for millennia, namely, that the gut is source of most, if not every issue, and so the locus of health and sickness, the better off we'll be. So many AI are thought or suspected to have a bacterial or yeast, etc. infection at their root that it only stands to reason.

If you suspect your gut as the source of the problem, then try it, or at least try to set things right first, via diet and probiotics. I intend to resort to this, if my diet, natural antibiotic and antifungal, and probiotic intervention doesn't work. You need a health donor, if you do it at home. Clinically, the studies have initially dealt with CD as noted, but more recently with UC (Ulcerative Colitus), equally successfully. For self-administered transplants, see "Success of Self-Administered Home Fecal Transplantation for Chronic Clostridium difficile Infection".

This is a very important issue, and can't be overemphasized, and the research is showing this more and more. What I've been wondering recently is whether correcting the gut issues, so Candida, SIBO, leaky gut, and eventually the microflora in the gut can reverse an AI issue, say my SFN. Assuming the bacteria has already caused its damage, won't healing the gut simply not cause further damage rather than reversing things? Or is the mechanism more complex, and I just can't see it at the moment. To be fair, I haven't been thinking about it seriously enough, and need to give it some good thought. Curious what people think.

I would say that anyone, ill or healthy, should take any gut issues seriously and address them immediately. Diet is the most important first step here, and a high carb/sugar diet is your worst enemy.

Cliffman 12-14-2015 02:51 PM

Quote:

Originally Posted by DavidHC (Post 1188382)
I've done a great deal of research on this topic over the years and have been following the research. MrsD is right, and there's more and more research being published. The sooner conventional medicine realizes what traditional medicine has known for millennia, namely, that the gut is source of most, if not every issue, and so the locus of health and sickness, the better off we'll be. So many AI are thought or suspected to have a bacterial or yeast, etc. infection at their root that it only stands to reason.

If you suspect your gut as the source of the problem, then try it, or at least try to set things right first, via diet and probiotics. I intend to resort to this, if my diet, natural antibiotic and antifungal, and probiotic intervention doesn't work. You need a health donor, if you do it at home. Clinically, the studies have initially dealt with CD as noted, but more recently with UC (Ulcerative Colitus), equally successfully. For self-administered transplants, see "Success of Self-Administered Home Fecal Transplantation for Chronic Clostridium difficile Infection".

This is a very important issue, and can't be overemphasized, and the research is showing this more and more. What I've been wondering recently is whether correcting the gut issues, so Candida, SIBO, leaky gut, and eventually the microflora in the gut can reverse an AI issue, say my SFN. Assuming the bacteria has already caused its damage, won't healing the gut simply not cause further damage rather than reversing things? Or is the mechanism more complex, and I just can't see it at the moment. To be fair, I haven't been thinking about it seriously enough, and need to give it some good thought. Curious what people think.

I would say that anyone, ill or healthy, should take any gut issues seriously and address them immediately. Diet is the most important first step here, and a high carb/sugar diet is your worst enemy.

Hi David,

For what it's worth here's one doctors take take on the subject; http://www.mayoclinic.org/healthy-li...e/faq-20058174

Cliffman :)

DavidHC 12-14-2015 02:58 PM

Thanks, Cliffman. Yes, of course, a practitioner of conventional medicine thinks as much. The reality is that the evidence is not lacking but studies, and the reason for that is that it's not profitable to the pharmaceutical companies, hence the lack of funding.

Regardless, studies, including clinical ones, are now showing that many suspected cases of Candida overgrowth are in fact cases of SIBO, and that it not Candida is at the rout of much, including IBS.


Quote:

Originally Posted by Cliffman (Post 1188388)
Hi David,

For what it's worth here's one doctors take take on the subject; http://www.mayoclinic.org/healthy-li...e/faq-20058174

Cliffman :)



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