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-   -   Has anybody heard anything about 'atexakin alfa' neuropathy treatment in development. (https://www.neurotalk.org/peripheral-neuropathy/228927-heard-atexakin-alfa-neuropathy-treatment-development.html)

Patrick Winter 11-20-2015 08:27 AM

Has anybody heard anything about 'atexakin alfa' neuropathy treatment in development.
 
A few months ago a promising treatment was said to be in development. I haven't heard much on it since then, has anyone? Maybe something to bring to our neurologists and ask...

http://www.pharmaceutical-technology...atment-4665940

mrsD 11-20-2015 09:04 AM

This is very interesting. However, I cannot find anything about it at the FDA or Orange Book. I suspect they will have a while yet to do that legal paperwork and perhaps trials.

madisongrrl 11-21-2015 02:10 AM

Just reading between the lines of the article it is likely that an IND has been filed and no holds have been placed by the FDA - especially if Merck Sorono has formed a partnership with this biotech company. It's not in the FDA Orange book because these in-licensing agreements tend to happen during the Phase II clinical trial stage. I'll try to check on this at work, but I would imagine it will be a while before we see Phase III results.

Patrick Winter 12-02-2015 12:10 PM

Quote:

Originally Posted by madisongrrl (Post 1184646)
Just reading between the lines of the article it is likely that an IND has been filed and no holds have been placed by the FDA - especially if Merck Sorono has formed a partnership with this biotech company. It's not in the FDA Orange book because these in-licensing agreements tend to happen during the Phase II clinical trial stage. I'll try to check on this at work, but I would imagine it will be a while before we see Phase III results.

I am sure if it was a cholesterol related drug they would express the approval of this.:mad:

madisongrrl 12-02-2015 12:52 PM

Quote:

Originally Posted by Patrick Winter (Post 1186454)
I am sure if it was a cholesterol related drug they would express the approval of this.:mad:

Yes, I looked into this a little bit - it's not being fast-tracked. I can't find a ton of info on it, but I did look at some of the animal studies on PubMed.

http://neurotalk.psychcentral.com/sh...12#post1186212

jurgen975 12-05-2015 05:16 PM

So did anybody find something in clinicaltrail.gov?This would be interesting to follow.

But i agree this is very interesting so there are now 2 drugs being developt

I also cant find the website from "Relief Therapeutics"

A explenation of what phases in clinical trails mean

http://biopharma.merckgroup.com/en/r...al_trials.html

European clinical trails
https://www.clinicaltrialsregister.e...opathy&page=19

madisongrrl 12-05-2015 11:24 PM

Phase 1 trials don't have to be reported for drugs or biologists on clinicaltrials.gov, so there won't be anything posted yet. (FDAAA801)

jurgen975 12-06-2015 06:05 AM

I have big a little bit deeper this is what i found til now

http://www.businesswire.com/news/hom...-Commercialize

In the above article interleukin-6 is mentioned so here you find what this stuff is all about
http://www.news-medical.net/health/W...rleukin-6.aspx

Relief Therapeutics looks like a one man company.. lead by Dr. Gael Hédou his telephone number and email adress are mention in the top article

But here is the linkedin adress
https://www.linkedin.com/pulse/relie...?trk=prof-post


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