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-   -   Ocrelizumab (https://www.neurotalk.org/multiple-sclerosis/233265-ocrelizumab.html)

SallyC 03-03-2016 08:41 AM

Ocrelizumab
 
http://acceleratedcure.org/sites/def...3.1.16.pdf.pdf

Sounds promising

agate 03-06-2016 12:42 PM

Yet another miracle drug being rolled out. Maybe this one will be better than the others!

kiwi33 03-06-2016 06:19 PM

Ocrelizumab is a humanised monoclonal antibody which blocks the action of a protein called CD20, found on mature B cells. Because of this it is immunosuppressive.

Phase 3 clinical trials of it in the context of MS look very encouraging. It is currently under consideration by the FDA for regulatory approval. There is more about this here; https://www.mssociety.org.uk/ms-rese...ne/ocrelizumab.

agate 03-06-2016 08:24 PM

Actually hasn't it been fast-tracked for speedier FDA approval?

kiwi33 03-06-2016 10:33 PM

Yes, it is on the "Breakthrough Therapy Designation" list.

SallyC 03-08-2016 11:22 AM

Hearing good things about this stuff. I hope they find it works for SPMS also.
Wouldn't that be nice?

kicker 04-26-2016 04:38 PM

Today read another promising thing about this, will also ask MS neurosuheon on May 13 John Hopkins doctor, for what that's worth.

kicker 04-26-2016 04:44 PM

As always, holding my breath, hoping.

Mcsisters 03-05-2017 01:04 PM

Made it into the Ocrelizumab study
 
Quote:

Originally Posted by kicker (Post 1209366)
Today read another promising thing about this, will also ask MS neurosuheon on May 13 John Hopkins doctor, for what that's worth.

Feeling anxious but blessed as my Neuro said I was going to have to switch medicines anyway. Jan1 I started a 100% work from .home job allowing me to work around doctors & tests. I am so happy to not be traveling alone for work anymore. After a few incidents on the road it just wasn't safe anymore. My first infusion is tomorrow so I am a bit anxious. I'll read through my things I signed to see if I am allowed to share my thoughts on it the next few years. If so, I will. Have a great day to all- hopefully one that is pain free as possible.

Mcsisters 03-14-2017 07:30 AM

1week in.....
 
I got a little light headed in the middle when I got up real fast (real fast is a relative term for me). But it was gone before the treatment was over. I didn't experience even the mild side effects. This alone was a blessing over the "flu like" side effects multiple times a week with Rebif. Next week I get the second half of the first dose. My fingers remain crossed.


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