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-   -   6% amitriptyline and 5% gabapentin cream (https://www.neurotalk.org/peripheral-neuropathy/233580-6-amitriptyline-5-gabapentin-cream.html)

baba222 03-10-2016 08:54 PM

6% amitriptyline and 5% gabapentin cream
 
Hello,
Taking 900mg gabapentin and 25 mg amitriptyline daily.

Now have the above cream prescribed.

May not be able to afford it, but want to try it at least once.

Can anyone tell me the milligrams of each of the above with this cream?

It will be a dosage tube of 90 grams.

Is it a straight percentage, 5.4 grams and 4.5 grams respectively?
TIA.

mrsD 03-10-2016 09:29 PM

Dosages in the creams are much different than oral.
This is because first pass thru the liver from the GI tract
Is bypassed .. They are not comparable.

Cliffman 03-11-2016 01:13 AM

Quote:

Originally Posted by baba222 (Post 1203700)
Hello,
Taking 900mg gabapentin and 25 mg amitriptyline daily.

Now have the above cream prescribed.

May not be able to afford it, but want to try it at least once.

Can anyone tell me the milligrams of each of the above with this cream?

It will be a dosage tube of 90 grams.

Is it a straight percentage, 5.4 grams and 4.5 grams respectively?
TIA.

If it's going to be very expensive you may want to ask the compounding pharmacy to give you a small amount. For example the pharmacy that I used wanted to charge $295 however I was able to try it out-of-pocket for $30 to make sure that it worked. Of course this was a sample size but it was enough for 10 days. Another thing that the pharmacy told me was to make sure that your doctor prescribes ketamine as one of the key ingredients. The ketamine is for pain control.

Hope this helps....
Cliffman :)

mrsD 03-11-2016 04:34 AM

Clonidine is also helpful for some people. This drug has been in final trials as a topical cream for chronic pain patients currently.

It can be sedating however.

http://www.ncbi.nlm.nih.gov/pubmed/26109991

However it looks like it won't be marketed any time soon.
http://www.biospace.com/News/biodeli...onidine/370481

A disadvantage of the compounded RX topicals is that most of them work best on small targeted areas like the feet or hands.
Applying them over the larger areas of the body, may be hugely expensive (needing large amounts) and also result in side effects of the absorbed drugs.

Have you tried the new Aspercreme Lidocaine? I find it very good for pain. So far I've used it on my knees and shins, and shoulder.

SylvieM 03-11-2016 06:52 AM

Aspertine lidocaine
 
Quote:

Have you tried the new Aspercreme Lidocaine? I find it very good for pain. So far I've used it on my knees and shins, and shoulder.
Last night was the first time I was truly bothered by neuropathic pain on my shins....it had only been my feet before. So is this cream good for this ....particularly paresthesias?

Thanks so much!


Sylvie

mrsD 03-11-2016 07:14 AM

Quote:

Originally Posted by SylvieM (Post 1203754)
Last night was the first time I was truly bothered by neuropathic pain on my shins....it had only been my feet before. So is this cream good for this ....particularly paresthesias?





Sylvie

Thanks so much!

Yes, I find it really good (it is also OTC)... as good as Lidoderm patches!

One application lasts me a day or so too. That aspect may vary with the individual, though.

SylvieM 03-11-2016 09:49 AM

Quote:

Originally Posted by mrsD (Post 1203756)
Thanks so much!

Yes, I find it really good (it is also OTC)... as good as Lidoderm patches!

One application lasts me a day or so too. That aspect may vary with the individual, though.

Great....I'll get it today....it's funny, last night I was wondering if there was a good OTC cream, and today, voila, my wishes were answered.

Thank you Mrs. D.....you are an invaluable resource!

Sylvie


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