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-   -   Doctors use deep-brain ultrasound to treat tremors (https://www.neurotalk.org/parkinson-s-disease/242847-doctors-deep-brain-ultrasound-treat-tremors.html)

eds195 12-10-2016 10:39 AM

Doctors use deep-brain ultrasound to treat tremors
 
We have seen this before, but it is very interesting and real.....

Doctors use deep-brain ultrasound therapy to treat tremors - BBC News

aftermathman 12-10-2016 02:40 PM

Ultrsound and MJFF ...
 
This looks like the best advance since ldopa, so I must have missed something.

I know MJFF are involved with this approach, testing it for tremor and dyskinesia, can someone, (perhaps from MJFF), summarise where we are with this and is it being targeted as a replacement for DBS ?

Neil.

zanpar321 12-11-2016 10:08 AM

Quote:

Originally Posted by aftermathman (Post 1230846)
This looks like the best advance since ldopa, so I must have missed something.

I know MJFF are involved with this approach, testing it for tremor and dyskinesia, can someone, (perhaps from MJFF), summarise where we are with this and is it being targeted as a replacement for DBS ?

Neil.

Isn't this similar to ablation only using sound instead of a hot probe? I'm not sure the results last long - only a few years. In time, the tremors return and you can't do it again.

Tupelo3 12-11-2016 11:14 AM

Quote:

Originally Posted by zanpar321 (Post 1230904)
Isn't this similar to ablation only using sound instead of a hot probe? I'm not sure the results last long - only a few years. In time, the tremors return and you can't do it again.

Actually, this is the ablation therapy you are thinking of. The high frequency ultrasound is what causes the heat that burns and destroys the targeted brain cells. It's works, it's approved(at least for essential tremor and being tested for PD tremor) and it's also non-invasive. On the other hand, as opposed to DBS, it's non-reversable.

eds195 12-11-2016 11:51 AM

Something I found even as interesting as the procedure itself is located in the bottom video at the 3:30 mark where he discusses opening up the narrow BBB entrance to allow easier and more efficient targeting. He doesn't say much but it could be an important step for meds and other treatments.

Eric

zanpar321 12-11-2016 09:11 PM

Quote:

Originally Posted by Tupelo3 (Post 1230907)
Actually, this is the ablation therapy you are thinking of. The high frequency ultrasound is what causes the heat that burns and destroys the targeted brain cells. It's works, it's approved(at least for essential tremor and being tested for PD tremor) and it's also non-invasive. On the other hand, as opposed to DBS, it's non-reversible.

That's what I thought. Too bad it isn't permanent. Seems like a false hope and permanent damage is done. DBS is reversable.

aftermathman 12-12-2016 10:17 AM

DBS is reversible ...
 
Quote:

Originally Posted by zanpar321 (Post 1230941)
That's what I thought. Too bad it isn't permanent. Seems like a false hope and permanent damage is done. DBS is reversable.

but I would go for non invasive ultrasound over DBS major surgery with the risks of stroke, bleeding and even death.

Now the tech is a lot more advanced the additional accuracy of destroying only those cells you need to gives ultrasound my vote.

Take care,
Neil.

zanpar321 12-12-2016 01:32 PM

Quote:

Originally Posted by aftermathman (Post 1230978)
but I would go for non invasive ultrasound over DBS major surgery with the risks of stroke, bleeding and even death.

Now the tech is a lot more advanced the additional accuracy of destroying only those cells you need to gives ultrasound my vote.

Take care,
Neil.

Ultrasound sounds great but I don't think the positive effects last but a few years and I don't know if you can have DBS at that point.

eds195 12-12-2016 04:30 PM

I don't know if it's false hope, permanent damage or only lasts a few years, or if they even know at this point. Maybe a professional reading these threads could shed some light.

zanpar321 12-12-2016 07:06 PM

Quote:

Originally Posted by eds195 (Post 1231019)
I don't know if it's false hope, permanent damage or only lasts a few years, or if they even know at this point. Maybe a professional reading these threads could shed some light.

My Neurologist tells me that ablation lasts only a couple years before the Parkinson's tremor returns. I suppose he could be wrong. I don't think the ultrasound trials have followed patients for more than a few years. I would love to hear a professional shed some light on this.


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