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-   -   Any Updates On MSDC-0160? (https://www.neurotalk.org/parkinson-s-disease/247582-updates-msdc-0160-a.html)

Blackfeather 06-16-2017 12:49 PM

Any Updates On MSDC-0160?
 
Here is one year and a half old link to this repurposed diabetes that showed promise in treating PD.
https://www.sciencedaily.com/release...1207143243.htm

kiwi33 06-17-2017 01:57 AM

This December 2016 paper reports some results for MSDC-0160, based of tissue culture, C. elegans and mouse models Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease | Science Translational Medicine.

Tupelo3 08-10-2017 10:24 AM

CPT Approves Funding for Research Investigation of MSDC-0160
 
Quote:

Originally Posted by Blackfeather (Post 1244881)
Here is one year and a half old link to this repurposed diabetes that showed promise in treating PD.
Diabetes drug slows experimental Parkinson's disease progression, human trials to begin next year -- ScienceDaily

Blackfeather, here is some new information on MSDC-0160. CPT will be funding more research, which will be done at the Van Andel Research Institute.

Cure Parkinson's Trust | CPT Approves Funding for Two Pre-clinical Studies of Anti-diabetic Drugs

Blackfeather 08-10-2017 01:40 PM

Thanks Tupe for the update. seems as though there is plethora of diabetes drugs being researched now for treating PD. Another diabetes drug being investigated that I reccently discovered is intranasal insulin. Maybe some of you folks are knowledgable about this one. Novolin R is a type of insulin being invesigated.
It bypasses the blood stream and crosses the BBB where it is taken up by insulin receptors in the brain. Its being investigated for treatment of Asheimer's disease and MSA as well. It's inexpensive and available now.
Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin. - Full Text View - ClinicalTrials.gov


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