Some Parkinson’s Patients May Benefit from Non-dopaminergic Treatments
Some Parkinson’s Patients May Benefit from Non-dopaminergic Treatments
Parkinson's Patients May Benefit from Non-dopaminergic Treatments |
Similar conclusions were quoted in a recent thread:
https://www.neurotalk.org/parkinson-...d-therapy.html 'Qamar et al. write ...: "Besides dopamine (DA), three further key neurotransmitters have been described to be involved in the pathogenesis of PD; namely noradrenaline (NA), acetylcholine (ACh), and serotonin (5HT)."' It doesn't seem unreasonable to think of Parkinson's as a neurotransmitter disease, rather than just a lack of dopamine disease. Moreover, the standard dopamine replacement therapy is throwing exogenous levodopa across the whole brain, which must have some effect on other neurotransmitters. Levodopa does a good job with motor problems, but does little to address non-motor symptoms such as constipation. John |
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