What else does Mestinon work on?
 

Aside from nerve gas poisoning, which obviously I could not have had for the last 16 years, what else does Mestinon work on? What else gets better when you take Mestinon, if it isn't MG?

What acts like MG but isn't?
What other diseases does mestinon provide improvement for, besides MG?

AChR negative. MuSK negative. Thyroid tests normal. Rheumatoid diseases blood tests normal/negative.

MG-like weaknesses, including dramatic eye problems, including breathing difficulties. Mestinon provides improvement that even casual acquaintances have noticed and commented on, it is so dramatic an effect.

So, if it's not MG, then what else could it be? Because without a positive test for something, my doctors are saying it's not MG. And started to suggest I should not be on mestinon, even tho it is obviously working so well for me.

Congenital myasthenic syndromes and LEMS (Lambert-Eaton Myasthenic Syndrome). Some ALS patients have temporary relief of symptoms, but that does not last.

One of the myasthenia gravis experts I saw at one of the teaching hospitals said that Mestinon also sometimes helps with fibromyalgia. I had not heard this.

Thanks, Erin. I read a study years ago about vagal tone being improved by Mestnon (similar to POTS).

A six-month randomized controlled trial of exercise and pyridostigmine in the treatment of fibromyalgia. - PubMed - NCBI

A Six-Month Randomized Controlled Trial of Exercise and Pyridostigmine in the Treatment of Fibromyalgia (Text of above article)

Impaired growth hormone secretion in fibromyalgia patients: evidence for augmented hypothalamic somatostatin tone. - PubMed - NCBI

A combination of 6 months of treatment with pyridostigmine and triweekly exercise fails to improve insulin-like growth factor-I levels in fibromyal... - PubMed - NCBI

Annie