Common Anti-inflammatory Medication May Help Prevent Parkinson’s Neurodegeneration
 

Common Anti-inflammatory Medication May Help Prevent Parkinson’s Neurodegeneration


Cosentyx May Prevent Parkinson's Neurodegeneration, Study Suggests

This seems to me to be a significant piece of work, and I'm hoping that AlzForum (or SoPD, or ...) do a writeup of it. The research is focused on a (possible) role for the adaptive immune system in the cause of neurodegeneration in PD.

Note that the innate immune system is also thought to (possibly) play a role in the cause of neurodegeneration in PD, and this is discussed in the following AlzForum article:

Does Taming Killer Astrocytes Spare Neurons in Parkinson’s Disease? | ALZFORUM

Here is the SoPD blog post on this research:

Keep your sights on lymphocytes | The Science of Parkinson's

There's a lot written about the possible therapeutic role of various anti-inflammatory drugs. For instance, we have aspirin and curcumin and, now, Cosentyx. My question is: do these different anti-inflammatory drugs add anything except in terms of volume? For instance, could we get all the benefit found using all the drugs just by taking more aspirin? If this is the case, then it is just a matter of convenience as to what drug to use. Of course, sometimes, the size of the dose becomes so large that its practical use becomes compromised. But, that aside, is it worth looking for more compounds? Or should we put to trial existing drugs?

John