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-   -   New pharmacokinetics and biomarker data from the Georgetown Nilotinib trial (https://www.neurotalk.org/parkinson-s-disease/253184-pharmacokinetics-biomarker-data-georgetown-nilotinib-trial.html)

Tupelo3 03-13-2019 01:47 PM

New pharmacokinetics and biomarker data from the Georgetown Nilotinib trial
 
Georgetown released some new pharmacokinetics and other biomarker data in a new report. Keep in mind it was just signal dose on small sample. I didn’t see anything groundbreaking here.

BPS Publications

ashleyk 03-14-2019 09:49 AM

?
 
I did a quick read on this. Did I miss anything on patient symptoms improving?

zanpar321 03-14-2019 10:29 AM

Quote:

Originally Posted by Tupelo3 (Post 1273377)
Georgetown released some new pharmacokinetics and other biomarker data in a new report. Keep in mind it was just signal dose on small sample. I didn’t see anything groundbreaking here.

BPS Publications

Some more data but what a waste of a study. I can't see how much can be learned from a single dose. No discussion of how this moved any up the road to approval/validation as a useful drug.

Tupelo3 03-14-2019 02:06 PM

Quote:

Originally Posted by ashleyk (Post 1273427)
I did a quick read on this. Did I miss anything on patient symptoms improving?

This was just pharmacokinetics and biomarker data analysis. We’re all still waiting for primary and secondary objective results which would give indications about efficacy. Some of the reported results in this article were very strange.


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