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-   -   Pacer review (https://www.neurotalk.org/als-news-and-research/256503-pacer-review.html)

MuonOne 02-21-2021 05:37 PM

Pacer review
 
I am working on a review of this intervention, which received FDA approval in 2011
These threads involve introductory discussion of the principle of operation and were available 2001 . . . :

Topic: Acetylcholine neurons - the ones that contact the mucle

Acetylcholine neurons - the ones that contact the mucle - BrainTalk Communities - Neurology Support Groups

Electrical device allows paralyzed man to breathe
Electrical device allows paralyzed man to breathe - BrainTalk Communities - Neurology Support Groups

MuonOne 02-25-2021 03:35 PM

The barren fact
 
DiPALS study survival medians were 28 months (pacer) , 45 months (NIV) . . . normal NIV survival is usually exceeds 36 months . . . thus, the question, 'Why were both results so poor?' remains open. RespiStimALS results were similar to the results used by the United States Food and Drug Administration to approve the treatment in Amyotrophic lateral Sclerosis.

MuonOne 02-25-2021 06:44 PM

Non-invasive ventilation in amyotrophic lateral sclerosis
 
Non-invasive ventilation in amyotrophic lateral sclerosis
Non-invasive ventilation in amyotrophic lateral sclerosis

In this report, several studies report NIV results of

"Accordingly, more recent retrospective studies with larger numbers of patients (n = 929, n = 114, n = 140) found survival benefits of 13 months,4 11 months,5 and 15.5 months,6 respectively."

Original finding place NIV at about 7 months.


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