NeuroTalk Support Groups

NeuroTalk Support Groups (https://www.neurotalk.org/)
-   Parkinson's Disease (https://www.neurotalk.org/parkinson-s-disease/)
-   -   Alternative delivery methods? (https://www.neurotalk.org/parkinson-s-disease/45004-alternative-delivery-methods.html)

Fiona 05-05-2008 12:28 PM

Alternative delivery methods?
 
Ok, maybe I'm missing something big that everyone else already knows about, but does anyone know why there are no such things as Sinemet inhalers or suppositories?

Fiona 05-05-2008 12:33 PM

Hmmmm.....
http://www.freepatentsonline.com/5750512.html

chasmo 05-05-2008 07:31 PM

the only one that is proven to work.....
 
is the pump made by a scandinavian company. It appears to work well.

Charlie

Fiona 05-05-2008 07:37 PM

Hey Charlie - what kinda pump? Stomach, nose.....
thanks, doll.
Fiona

ol'cs 05-05-2008 09:32 PM

hardly an..
 
alternative delivery method, but i'm using Parcopa. It banishes an off within 15 minutes on an empty stomach, and it's tasty!

lou_lou 05-05-2008 10:48 PM

dearest cs - hello!
 
Quote:

Originally Posted by ol'cs (Post 273516)
alternative delivery method, but i'm using Parcopa. It banishes an off within 15 minutes on an empty stomach, and it's tasty!

dear cs,
you know that the tasty part is aspartame, a neurotoxin?
I called the company - asking them to remove it - but there is no way - I can take it - horrid headaches, - too...
hope, and peace to you,
:hug:

chasmo 05-06-2008 12:41 AM

Quote:

Originally Posted by chasmo (Post 273422)
is the pump made by a scandinavian company. It appears to work well.

Charlie

it is a pump buried in the stomach area and it feeds into the duodnum (sp) the small intestine near the stomach.

Charlie

Fiona 05-06-2008 05:58 AM

SO it would be helpful to know from people if you have NEVER heard of Sinemet being administered rectally, through nasal passages, vaginally, intravenously or whatever. If people have never heard of this phenomenon, then it makes me wonder how much those possibilities have even been considered. Unless there's some big obvious reason why not that I haven't thought of but everybody else knows...

I ask this because an ER doctor recently suggested to me that a Benadryl suppository would act much faster in an instance of dystonia. It made me think about all the other possibilities...

lurkingforacure 05-06-2008 08:57 AM

levadopa patch
 
Hi all,

We have been watching for more news of this since we first read of it, here's the latest info. we have...this is NOT the Neupro patch that was recently recalled but, rather, an actual patch that delivers levadopa....

Israel’s NeuroDerm raises $2.5M for patch-based Parkinson’s drug
David P. Hamilton | July 24th, 2007 |
Israel’s NeuroDerm (the page is currently a placeholder), a biotech developing drug patches for neurological disorders such as Parkinson’s disease, raised $2.5 million in a first round of funding. The investment was provided by private individuals, including Robert Taub, founder and CEO of Omrix Pharmaceuticals.

NeuroDerm, based in Ofakim, Israel, is at work on a skin patch that will allow continuous delivery of levadopa, a drug now used to treat Parkinson’s. Continuous delivery of the drug may help many patients avoid motor complications, the company says.

paula_w 05-06-2008 09:55 AM

There is a clinical trial coming to the U.S. by Solvay that uses an intestinal pump for continuous l-dopa infusion. It's been used in Europe for quite a while. There have been difficulties working it out with the FDA. It will be a Phase III trial and the treatment is called Duodopa. FDA is insisting on a sham surgery trial.

http://www.solvaypharmaceuticals.com...641-2-0,00.htm

I have heard "things" about inhalants, but not sure it's l-dopa and can't share it because i don't know any more than that. Competition is very stiff, and the researcher was not at liberty to discuss. I think it's pretty safe to say they are researching those possibilities. Researcher said he may have something to talk about later this year.

paula


All times are GMT -5. The time now is 11:07 AM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.